Increasing the angiotensin converting enzyme inhibitory activity of goat milk hydrolysates by cross-flow filtration through ceramic membranes

被引：2

作者：

Javier Espejo-Carpio, Francisco ^{[1
]}

Perez-Galvez, Raul ^{[1
]}

del Carmen Almecija, Maria ^{[1
]}

Guadix, Antonio ^{[1
]}

Maria Guadix, Emilia ^{[1
]}

机构：

[1] Univ Granada, Dept Chem Engn, E-18071 Granada, Spain

来源：

Desalination and Water Treatment | 2015年 / 56卷 / 13期

关键词：

Goat milk; Protein hydrolysis; ACE inhibitory activity; Ceramic membrane; PROTEIN HYDROLYSATE; JUICE CLARIFICATION; PEPTIDES; ULTRAFILTRATION; IDENTIFICATION; FRACTIONATION; PURIFICATION; CONCENTRATE; PERFORMANCE; SEPARATION;

D O I：

10.1080/19443994.2014.985729

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

In this work, goat milk proteins were hydrolyzed by different treatments consisting sequential or simultaneous combinations of subtilisin and trypsin. The hydrolysate showing the highest angiotensin converting enzyme (ACE) inhibitory activity was submitted to ultrafiltration in the concentration mode through tubular ceramic membranes of 50 and 15kDa. The time evolution of the permeate flux was fitted to several models in order to identify the most feasible fouling mechanisms. The retentates and the permeates obtained after reaching a concentration factor of 3 were tested for their ACE inhibitory activity. Good enhancements were determined in the case of the permeates. Finally, the cleaning of the membrane with sodium hydroxide was successfully assayed.

引用

页码：3544 / 3553

页数：10

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