Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex in Patients with Optic Neuritis or Neuromyelitis Optica Spectrum Disorders Using Optical Coherence Tomography in a Chinese Cohort

被引:18
作者
Tian, Guohong [1 ]
Li, Zhenxin [2 ]
Zhao, Guixian [2 ]
Feng, Chaoyi [1 ]
Li, Mengwei [1 ]
Huang, Yongheng [1 ]
Sun, Xinghuai [1 ]
机构
[1] Fudan Univ, Eye Ear Nose & Throat Hosp, Dept Ophthalmol, Shanghai 200031, Peoples R China
[2] Fudan Univ, Huashan Hosp, Dept Neurol, Shanghai 200031, Peoples R China
关键词
MULTIPLE-SCLEROSIS;
D O I
10.1155/2015/832784
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
We evaluate a cohort of optic neuritis and neuromyelitis optica (NMO) spectrum disorders patients in a territory hospital in China. Theperipapillary retinal nerve fiber layer (RNFL) andmacular ganglion cell complex (GCC) were measured using spectral-domain OCT after 6 months of acute onset. The results showed that both the peripapillary RNFL and macular GCC were significantly thinner in all optic neuritis subtypes compared to controls. In addition, the recurrent optic neuritis and NMO groups showed more severe damage on the RNFL and GCC pattern.
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页数:6
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