Chitosan-pectin-alginate as a novel scaffold for tissue engineering applications

被引：0
作者：
Archana, D. [1 ]
Upadhyay, Laxmi [2 ]
Tewari, R. P. [2 ]
Dutta, Joydeep [3 ]
Huang, Y. B. [4 ]
Dutta, P. K. [1 ]
机构：
[1] MN Natl Inst Technol, Dept Chem, Allahabad 211004, Uttar Pradesh, India
[2] MN Natl Inst Technol, Dept Appl Mech, Allahabad 211004, Uttar Pradesh, India
[3] Inst Engn & Technol, Dept Chem, Raipur 493661, Madhya Pradesh, India
[4] Changchun Inst Appl Chem, Changchun, Peoples R China
来源：
INDIAN JOURNAL OF BIOTECHNOLOGY | 2013年 / 12卷 / 04期
关键词：
Alginate; cell viability; chitosan; lyophilization; pectin; scaffolds; tissue engineering; IN-VITRO; CONTROLLED-RELEASE; HYALURONIC-ACID; DERIVATIVES; BEHAVIOR; VIVO;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Chitosan-pectin, chitosan-alginate and chitosan-pectin-alginate scaffolds were prepared by freeze-drying technique. The physicochemical characteristics of the scaffolds were characterized by FTIR and SEM. The biological activities like antibacterial assessment, swelling behavior, biodegradation and cytotoxicity study of the prepared scaffolds were evaluated. The results show high swelling property, good mechanical strength, moderate biodegradable properties, excellent antibacterial activity and cell-viability for chitosan-pectin-alginate ternary scaffold. Hence, it can be served as a potential material for tissue engineering applications.
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页码：475 / 482
页数：8
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