Chitosan-pectin-alginate as a novel scaffold for tissue engineering applications

被引：0

作者：

Archana, D. ^{[1
]}

Upadhyay, Laxmi ^{[2
]}

Tewari, R. P. ^{[2
]}

Dutta, Joydeep ^{[3
]}

Huang, Y. B. ^{[4
]}

Dutta, P. K. ^{[1
]}

机构：

[1] MN Natl Inst Technol, Dept Chem, Allahabad 211004, Uttar Pradesh, India

[2] MN Natl Inst Technol, Dept Appl Mech, Allahabad 211004, Uttar Pradesh, India

[3] Inst Engn & Technol, Dept Chem, Raipur 493661, Madhya Pradesh, India

[4] Changchun Inst Appl Chem, Changchun, Peoples R China

来源：

INDIAN JOURNAL OF BIOTECHNOLOGY | 2013年 / 12卷 / 04期

关键词：

Alginate; cell viability; chitosan; lyophilization; pectin; scaffolds; tissue engineering; IN-VITRO; CONTROLLED-RELEASE; HYALURONIC-ACID; DERIVATIVES; BEHAVIOR; VIVO;

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Chitosan-pectin, chitosan-alginate and chitosan-pectin-alginate scaffolds were prepared by freeze-drying technique. The physicochemical characteristics of the scaffolds were characterized by FTIR and SEM. The biological activities like antibacterial assessment, swelling behavior, biodegradation and cytotoxicity study of the prepared scaffolds were evaluated. The results show high swelling property, good mechanical strength, moderate biodegradable properties, excellent antibacterial activity and cell-viability for chitosan-pectin-alginate ternary scaffold. Hence, it can be served as a potential material for tissue engineering applications.

引用

页码：475 / 482

页数：8

共 27 条

[1]

Archana D., 2010, Asian Chitin J, V6, P45

[2] Study of the interpolyelectrolyte reaction between chitosan and alginate:: influence of alginate composition and chitosan molecular weight [J].

Becherán-Marón, L ;

Peniche, C ;

Argüelles-Monal, W .

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2004, 34 (1-2) :127-133

[3] Osteoblastic response to collagen scaffolds varied in freezing temperature and glutaraldehyde crosslinking [J].

Chen, Dai-Chian ;

Lai, Yu-Lin ;

Lee, Shyh-Yuan ;

Hung, Shan-Ling ;

Chen, Hen-Li .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2007, 80A (02) :399-409

[4] Preparation and chemical and biological characterization of a pectin/chitosan polyelectrolyte complex scaffold for possible bone tissue engineering applications [J].

Coimbra, P. ;

Ferreira, P. ;

de Sousa, H. C. ;

Batista, P. ;

Rodrigues, M. A. ;

Corriea, I. J. ;

Gil, M. H. .

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2011, 48 (01) :112-118

[5]

Dutta J., 2005, CHITIN CHITOSAN OPPO, P1

[6] Chitosan disrupts the barrier properties of the outer membrane of Gram-negative bacteria [J].

Helander, IM ;

Nurmiaho-Lassila, EL ;

Ahvenainen, R ;

Rhoades, J ;

Roller, S .

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2001, 71 (2-3) :235-244

[7] Oligoamines conjugated chitosan derivatives: Synthesis, characterization, in vitro and in vivo biocompatibility evaluations [J].

Jia, Yi ;

Hu, Yingqian ;

Zhu, Yuxuan ;

Che, Ling ;

Shen, Qiying ;

Zhang, Jianxiang ;

Li, Xiaohui .

CARBOHYDRATE POLYMERS, 2011, 83 (03) :1153-1161

[8] Water state characterization, swelling behavior, thermal and mechanical properties of chitosan based networks [J].

Khalid, MN ;

Agnely, F ;

Yagoubi, N ;

Grossiord, JL ;

Couarraze, G .

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2002, 15 (05) :425-432

[9] Chitosan and its derivatives for tissue engineering applications [J].

Kim, In-Yong ;

Seo, Seog-Jin ;

Moon, Hyun-Seuk ;

Yoo, Mi-Kyong ;

Park, In-Young ;

Kim, Bom-Chol ;

Cho, Chong-Su .

BIOTECHNOLOGY ADVANCES, 2008, 26 (01) :1-21

[10] The preparation and characterisation of drug-loaded alginate and chitosan sponges [J].

Lai, HL ;

Abu'Khalil, A ;

Craig, DQM .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2003, 251 (1-2) :175-181

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