Neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failure

被引:26
作者
Turfan, Murat [1 ]
Erdogan, Ercan [1 ]
Tasal, Abdurrahman [1 ]
Vatankulu, Mehmet Akif [1 ]
Jafarov, Parviz [1 ]
Sonmez, Osman [1 ]
Ertas, Gokhan [1 ]
Bacaksiz, Ahmet [1 ]
Goktekin, Omer [1 ]
机构
[1] Bezmialem Univ, Fac Med, Dept Cardiol, Istanbul, Turkey
关键词
Neutrophil-to-Lymphocyte Ratio; Mortality; Acute Heart Failure; LONG-TERM MORTALITY; ELEVATION MYOCARDIAL-INFARCTION; CORONARY INTERVENTION; PREDICTORS; COUNT; PATHOPHYSIOLOGY; INFLAMMATION; DYSFUNCTION;
D O I
10.6061/clinics/2014(03)08
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVES: Previous studies have demonstrated the role of inflammation in acute heart failure. The neutrophil-to-lymphocyte ratio was found to be a useful inflammatory marker for predicting adverse outcomes. We hypothesized that an elevated neutrophil-to-lymphocyte ratio would be associated with increased mortality in acute heart failure patients. METHODS: The study cohort consisted of 167 acute heart failure patients with an ejection fraction <50%. The primary endpoint was in-hospital mortality, and the patients were divided into two groups according to in hospital mortality. RESULTS: In a multivariate regression analysis, including baseline demographic, clinical, and biochemical covariates, the neutrophil to lymphocyte ratio remained an independent predictor of mortality (OR 1.156, 95% CI 1.001 - 1.334, p = 0.048). CONCLUSION: In conclusion, an elevated neutrophil-to-lymphocyte ratio seems to be a predictor of short-term mortality in patients with acute heart failure and a reduced left ventricular ejection fraction.
引用
收藏
页码:190 / 193
页数:4
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