Blast crisis of chronic myeloid leukemia: Diagnosis prompted by T(8;9)

被引：5

作者：

Borker, A

Yu, L

Ode, D

机构：

[1] Louisiana State Univ, Hlth Sci Ctr, Dept Pediat Hematol Oncol, Childrens Hosp New Orleans, New Orleans, LA 70118 USA

[2] Childrens Hosp New Orleans, Dept Pediat Hematol Oncol, New Orleans, LA USA

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2002年 / 24卷 / 08期

关键词：

CML; AML; translocation (t : 8,9); bcr/abl; PCR;

D O I：

10.1097/00043426-200211000-00014

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

T(8;9) is a relatively new translocation that has been reported in a few patients with chronic myeloid leukemia (CML) but never in acute myeloid leukemia (AML). We report here a patient who presented with AML with t(8; 9). He lacked the Philadelphia chromosome but tested positive for the bcr/abl gene by the polymerase chain reaction method. This confirmed the diagnosis of CML with blast crisis, and appropriate treatment could be instituted.

引用

页码：670 / 671

页数：2

共 6 条

[1] A NEW TRANSLOCATION INVOLVING CHROMOSOME-8 AND CHROMOSOME-9 IN A PHILADELPHIA-NEGATIVE CHRONIC MYELOGENOUS LEUKEMIA
BOTTI, AC
SILVER, RT
MACERA, MJ
BENN, P
VERMA, RS
[J]. CANCER GENETICS AND CYTOGENETICS, 1988, 35 (01) : 51 - 54
[2] NOVEL RECIPROCAL TRANSLOCATION BETWEEN CHROMOSOME-8 AND CHROMOSOME-9 FOUND IN A PATIENT WITH MYELOPROLIFERATIVE DISORDER
FRIEDHOFF, F
RAJENDRA, B
MOODY, R
ALAPATT, T
[J]. CANCER GENETICS AND CYTOGENETICS, 1983, 9 (04) : 391 - 394
[3] HIDEKI N, 1996, BRIT J HAEMATOL, V92, P692
[4] LEWIS JP, 1983, AM J PEDIAT HEMATOL, V5, P265
[5] Muhlematter D, 1992, BRIT J HAEMATOL, V81, P307
[6] RECIPROCAL TRANSLOCATION BETWEEN CHROMOSOME-8 AND CHROMOSOME-9 IN ATYPICAL CHRONIC MYELOID-LEUKEMIA
OSCIER, DG
MUFTI, GJ
GARDINER, A
HAMBLIN, TJ
[J]. JOURNAL OF MEDICAL GENETICS, 1985, 22 (05) : 398 - 401

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