3,4-bis(trimethylsilyl)-1H-pyrrole: a versatile building block for unsymmetrically 3,4-disubstituted pyrroles

被引：25

作者：

Chan, HW ^{[1
]}

Chan, PC ^{[1
]}

Liu, JH ^{[1
]}

Wong, HNC ^{[1
]}

机构：

[1] CHINESE UNIV HONG KONG,DEPT CHEM,SHATIN,NEW TERR,HONG KONG

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 16期

关键词：

D O I：

10.1039/a703921b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3,4-Bis(trimethylsilyl)-1H-pyrrole 1c functions as a versatile building block for the construction of unsymmetrically 3,4-disubstituted pyrroles through the use of stepwise regiospecific ipso mono-halogenation, Sonogashira cross-coupling reactions and Suzuki cross-coupling reactions; the advantages of this strategy lie in its stepwise manner as well as in its prospect of yielding 3,4-disubstituted pyrroles with diverse substitution patterns.

引用

页码：1515 / 1516

页数：2

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