How Bacteria Use Type IV Pili Machinery on Surfaces

被引：146

作者：

Maier, Berenike ^{[1
]}

Wong, Gerard C. L. ^{[2
]}

机构：

[1] Univ Cologne, Dept Phys, D-50937 Cologne, Germany

[2] Univ Calif Los Angeles, Calif Nano Syst Inst, Dept Chem & Biochem, Dept Bioengn, Los Angeles, CA 90095 USA

来源：

TRENDS IN MICROBIOLOGY | 2015年 / 23卷 / 12期

基金：

美国国家科学基金会;

关键词：

PSEUDOMONAS-AERUGINOSA PSL; TUG-OF-WAR; TWITCHING MOTILITY; DEVELOPMENTAL BIOLOGY; NEISSERIA-GONORRHOEAE; BIOFILM FORMATION; GLIDING MOTILITY; SOCIAL MOTILITY; FLAGELLA; RETRACTION;

D O I：

10.1016/j.tim.2015.09.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The bacterial type IV pilus (T4P) is a versatile molecular machine with a broad range of functions. Recent advances revealed that the molecular components and the biophysical properties of the machine are well conserved among phylogenetically distant bacterial species. However, its functions are diverse, and include adhesion, motility, and horizontal gene transfer. This review focusses on the role of T4P in surface motility and bacterial interactions. Different species have evolved distinct mechanisms for intracellular coordination of multiple pili and of pill with other motility machines, ranging from physical coordination to biochemical clocks. Coordinated behavior between multiple bacteria on a surface is achieved by active manipulation of surfaces and modulation of pilus-pilus interactions. An emerging picture is that the T4P actively senses and responds to environmental conditions.

引用

页码：775 / 788

页数：14

共 108 条

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