Peltophorum pterocarpum Flower-Mediated Synthesis, Characterization, Antimicrobial and Cytotoxic Activities of ZnO Nanoparticles

被引:19
作者
Khara, Gunjan [1 ]
Padalia, Hemali [1 ]
Moteriya, Pooja [1 ]
Chanda, Sumitra [1 ]
机构
[1] Saurashtra Univ, Dept Biosci UGC CAS, Rajkot 360005, Gujarat, India
关键词
Green synthesis; Peltophorum pterocarpum; Zinc oxide nanoparticles; Antimicrobial activity; Cytotoxic activity; ZINC-OXIDE NANOPARTICLES; LEAF EXTRACT; GREEN SYNTHESIS; ANTIBACTERIAL ACTIVITY; SILVER NANOPARTICLES; ANTIOXIDANT; ANTIFUNGAL; AGENTS; SIZE;
D O I
10.1007/s13369-017-2875-6
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
In the present investigation, zinc oxide nanoparticles (ZnONPs) were synthesized using Peltophorum pterocarpum flower extract and evaluated its antimicrobial and cytotoxic activity. The synthesis of ZnONPs using plant extracts is becoming popular as it is eco-friendly, safe, simple and non-toxic method. Characterization was done by various spectral analyses. UV-visible spectrum showed maximum peak at 380 nm, and crystalline nature was of nanoparticles confirmed by XRD analysis. The average size of nanoparticles was 69.45 nm. The antimicrobial activity was evaluated by agar well diffusion method against pathogenic microorganisms. ZnONPs showed broad spectrum of antimicrobial activity against pathogenic microorganisms. Cytotoxic activity was evaluated by MTT assay against HeLa cancer cell lines. They showed 50% cell viability at . The results suggested that synthesized ZnONPs have potential application in various field of medical for treatment of disease.
引用
收藏
页码:3393 / 3401
页数:9
相关论文
共 36 条
[1]  
Akash S., 2015, INT J PHARM BIOSCIEN, V6, P85
[2]   Effect of various capping agents on photocatalytic, antibacterial and antibiofilm activities of ZnO nanoparticles [J].
Akhil, K. ;
Jayakumar, J. ;
Gayathri, G. ;
Khan, S. Sudheer .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2016, 160 :32-42
[3]  
Anbukkarasi V, 2015, Int. J. Pharm. Sci. Rev. Res, V33, P110
[4]  
[Anonymous], 2011, ADV MAT LETT, DOI DOI 10.5185/AMLETT.INDIAS.204
[5]  
[Anonymous], MICROBIAL PATHOGENS
[6]  
Brown Karen, 2002, Expert Opin Drug Saf, V1, P253, DOI 10.1517/14740338.1.3.253
[7]   Antimicrobial Properties of a Novel Silver-Silica Nanocomposite Material [J].
Egger, Salome ;
Lehmann, Rainer P. ;
Height, Murray J. ;
Loessner, Martin J. ;
Schuppler, Markus .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2009, 75 (09) :2973-2976
[8]   Green synthesis, characterization and antimicrobial activities of zinc oxide nanoparticles from the leaf extract of Azadirachta indica (L.) [J].
Elumalai, K. ;
Velmurugan, S. .
APPLIED SURFACE SCIENCE, 2015, 345 :329-336
[9]   Morphology and antifungal effect of nano-ZnO and nano-Pd-doped nano-ZnO against Aspergillus and Candida [J].
Gondal, Mohammed A. ;
Alzahrani, Alhusain J. ;
Randhawa, Mohammad A. ;
Siddiqui, Mohammad N. .
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, 2012, 47 (10) :1413-1418
[10]   Synthesis, characteristics and antimicrobial activity of ZnO nanoparticles [J].
Janaki, A. Chinnammal ;
Sailatha, E. ;
Gunasekaran, S. .
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2015, 144 :17-22