Incidence of Hypercoagulable Events after Image-Guided Percutaneous Cryoablation of Renal Tumors: A Single-Center Experience

Purpose: To identify retrospectively hypercoagulable events that occurred over time in patients who underwent image-guided percutaneous renal cryoablation and compare the incidence with a cohort of patients who underwent surgical partial nephrectomy (PN) during the same nine period. Materials and Methods: An electronic medical record database was queried for patients who underwent percutaneous image-guided renal mass cryoablation or PN between September 2006 and June 2012. Records were examined for thrombotic events during the year following the procedure in each group. Incidence rates, Kaplan-Meier estimates, and patient. demographic variables were compared using the stratified log-rank test and t test for independent samples. Results: The study comprised 114 cryoablation cases. The cumulative incidence of thrombotic events after 1 year was 4.39%. The incidence per 100 person years was 4.84. There were 105 PN oases. The cumulative incidence of thrombotic,events after 1 year Was 1.0%. The incidence per no person-years was 1.14. The person-time incidence rate difference for these two groups did not reach statistical significance (P = .0894). Conclusions: The incidence of thrombotic events in patients who underwent percutaneous renal cryoablation in this study was not significantly different than a comparable cohort who underwent surgical PN during the same time period.