Modulation of the N30 generators of the somatosensory evoked potentials by the mirror neuron system

被引:25
作者
Cebolla, A. M. [1 ]
Palmero-Soler, E. [2 ]
Dan, B. [3 ]
Cheron, G. [1 ,2 ]
机构
[1] Univ Libre Bruxelles, LNMB, Neurosci Inst UNL, Brussels, Belgium
[2] Univ Mons, Lab Electrophysiol, B-7000 Mons, Belgium
[3] Univ Libre Bruxelles, Dept Neurol, Hop Univ Enfants Reine Fabiola, Brussels, Belgium
关键词
TRANSCRANIAL MAGNETIC STIMULATION; EVENT-RELATED DYNAMICS; PRIMARY MOTOR CORTEX; MEDIAN NERVE; BIOLOGICAL MOTION; FRONTAL COMPONENT; PREMOTOR CORTEX; PHASE-LOCKING; TOOL USE; BRAIN;
D O I
10.1016/j.neuroimage.2014.03.039
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The N30 component of the somatosensory evoked potential is known to be modulated by sensory interference, motor action, movement ideation and observation. We introduce a new paradigm in which the observation task Of another person's hand movement triggers the somatosensory stimulus, inducing the N30 response in participants. In order to identify the possible contribution of the mirror neuron network (MNN) to this early sensorimotor processing, we analyzed the N30 topography, the event-related spectral perturbation and the inter-trial coherence on single electroencephalogram (EEG) trials, and we applied swLORETA to localize the N30 sources implicated in the time-frequency domain at rest and during observation, as well as the generators differentiating these two contextual brain states. We found that N30 amplitude increase correlated with increased contralateral precentral alpha, frontal beta, and contralateral frontal gamma power spectrum, and with central and precentral alpha and parietal beta phase-locking of ongoing EEG signals. We demonstrate specific activation of the contralateral post-central and parietal cortex where the angular gyrus (BA39), an important MNN node, is implicated in this enhancement during observation. We conclude that this part of the MNN, involved in proprioceptive processing and more complex body-action representations, is already active prior to somatosensory input and may enhance N30. (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:48 / 60
页数:13
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