Catch and release microwave mediated synthesis of cyanine dyes

被引:43
作者
Lopalco, Maria [1 ]
Koini, Eftychia N. [2 ]
Cho, Jin Ku [1 ]
Bradley, Mark [1 ]
机构
[1] Univ Edinburgh, Sch Chem, Edinburgh EH9 3JJ, Midlothian, Scotland
[2] Natl Hellen Res Fdn, Athens 11635, Greece
关键词
FLUORESCENT-PROBES;
D O I
10.1039/b820719b
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Unsymmetrical functionalised cyanine dyes, covering the whole colour range, were readily synthesised (in 100 mg amounts) by a combination of microwave and solid-phase methodologies.
引用
收藏
页码:856 / 859
页数:4
相关论文
共 24 条
[1]   Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands [J].
Becker, A ;
Hessenius, C ;
Licha, K ;
Ebert, B ;
Sukowski, U ;
Semmler, W ;
Wiedenmann, B ;
Grötzinger, C .
NATURE BIOTECHNOLOGY, 2001, 19 (04) :327-331
[2]   Novel water-soluble near-infrared cyanine dyes:: Synthesis, spectral properties, and use in the preparation of internally quenched fluorescent probes [J].
Bouteiller, Cedric ;
Clave, Guillaume ;
Bernardin, Aude ;
Chipon, Bertrand ;
Massonneau, Marc ;
Renard, Pierre-Yves ;
Romieu, Anthony .
BIOCONJUGATE CHEMISTRY, 2007, 18 (04) :1303-1317
[3]   Cyanine dye conjugates as probes for live cell imaging [J].
Carreon, Jay R. ;
Stewart, Kelly M. ;
Mahon, Kerry P., Jr. ;
Shin, Stephanie ;
Kelley, Shana O. .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (18) :5182-5185
[4]   In vivo near-infrared fluorescence imaging of integrin a,αvβ3 in brain tumor xenografts [J].
Chen, XY ;
Conti, PS ;
Moats, RA .
CANCER RESEARCH, 2004, 64 (21) :8009-8014
[5]   Beyond six colors: A new era in flow cytometry [J].
De Rosa, Stephen C. ;
Brenchley, Jason M. ;
Roederer, Mario .
NATURE MEDICINE, 2003, 9 (01) :112-117
[6]   Novel cyanine dye-labeled dideoxynucleoside triphosphates for DNA sequencing [J].
Duthie, RS ;
Kalve, IM ;
Samols, SB ;
Hamilton, S ;
Livshin, I ;
Khot, M ;
Nampalli, S ;
Kumar, S ;
Fuller, CW .
BIOCONJUGATE CHEMISTRY, 2002, 13 (04) :699-706
[7]   In vivo near-infrared fluorescence imaging [J].
Frangioni, JV .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2003, 7 (05) :626-634
[8]   Synthesis and reactivities of 3-indocyanine-green-acyl-1,3-thiazolidine-2-thione (ICG-ATT) as a new near-infrared fluorescent-labeling reagent [J].
Hirata, T ;
Kogiso, H ;
Morimoto, K ;
Miyamoto, S ;
Taue, H ;
Sano, S ;
Muguruma, N ;
Ito, S ;
Nagao, Y .
BIOORGANIC & MEDICINAL CHEMISTRY, 1998, 6 (11) :2179-2184
[9]   Solid-phase synthesis of asymmetric cyanine dyes [J].
Isacsson, J ;
Westman, G .
TETRAHEDRON LETTERS, 2001, 42 (18) :3207-3210
[10]   Long-term multiple color imaging of live cells using quantum dot bioconjugates [J].
Jaiswal, JK ;
Mattoussi, H ;
Mauro, JM ;
Simon, SM .
NATURE BIOTECHNOLOGY, 2003, 21 (01) :47-51