Delayed exstrophy repair (DER) does not compromise initial bladder development

被引:15
作者
Ferrara, Francesco [1 ]
Dickson, Alan P. [1 ]
Fishwick, Janet [1 ]
Vashisht, Rita [2 ]
Khan, Tahair [3 ]
Cervellione, Raimondo M. [1 ]
机构
[1] Royal Manchester Childrens Hosp, Dept Paediat Urol, Manchester M13 9WL, Lancs, England
[2] Royal Manchester Childrens Hosp, Dept Paediat Anaesthesia, Manchester M13 9WL, Lancs, England
[3] Royal Manchester Childrens Hosp, Dept Paediat Orthopaed, Manchester M13 9WL, Lancs, England
关键词
Bladder exstrophy; Bladder growth; Delayed repair; CLOSURE; MANAGEMENT;
D O I
10.1016/j.jpurol.2013.10.026
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Objective: Delayed exstrophy repair (DER) represents an alternative to early neonatal bladder closure. This study aims to define the consequence of DER on bladder growth in bladder exstrophy patients who underwent routine DER, compared with those who underwent immediate postnatal reconstruction. Methods: Between 2000 and 2005, classic bladder exstrophy patients referred to the authors' institution underwent early neonatal bladder closure (group 1). Subsequently, classic bladder exstrophy patients referred to the authors' institution were treated with an elective DER (group 2). Bladder capacity was assessed between the age of 1 and 4 years with an unconscious cystogram. When dilating VUR was present, the volume of the contrast migrated into the ureter was calculated and subtracted. Results: Sixty patients were treated between 2000 and 2012. Complete follow-up data were available for 45 patients and they were included in the study: 21 in group 1 (11 males) and 24 in group 2 (14 males). The mean (SD) bladder volumes were 72.85 (28.5) ml in group 1 and 72.87 (34.9) in group 2 (p = 0.99). Conclusion: In the authors' experience, DER does not reduce the subsequent bladder capacities compared with neonatal exstrophy closure. (C) 2013 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:506 / 510
页数:5
相关论文
共 16 条
[1]  
AADALEN RJ, 1980, CLIN ORTHOP RELAT R, P193
[2]  
Baird A D, 2005, J Pediatr Urol, V1, P31, DOI 10.1016/j.jpurol.2004.09.001
[3]   Delayed Primary Repair of Bladder Exstrophy: Ultimate Effect on Growth [J].
Baradaran, Nima ;
Cervellione, Raimondo M. ;
Stec, Andrew A. ;
Gearhart, John P. .
JOURNAL OF UROLOGY, 2012, 188 (06) :2336-2341
[4]   Bilateral Ureteral Reimplantation at Primary Bladder Exstrophy Closure [J].
Braga, Luis H. P. ;
Lorenzo, Armando J. ;
Jrearz, Ricky ;
Bagli, Darius J. ;
Salle, Joao L. Pippi .
JOURNAL OF UROLOGY, 2010, 183 (06) :2337-2341
[5]   Penile ischemic injury in the exstrophy/epispadias spectrum: New insights and possible mechanisms [J].
Cervellione, Raimondo M. ;
Husmann, Douglas A. ;
Bivalacqua, Trinity J. ;
Sponseller, Paul D. ;
Gearhart, John P. .
JOURNAL OF PEDIATRIC UROLOGY, 2010, 6 (05) :450-456
[6]  
Cervellione RM, 2010, ANN INT C BRIT ASS P
[7]  
Cervellione RM, 2009, 3 INT BLADD EXSTR S
[8]   DELAYED SURGERY FOR CONGENITAL DIAPHRAGMATIC-HERNIA - NEURODEVELOPMENTAL OUTCOME IN LATER CHILDHOOD [J].
DAVENPORT, M ;
RIVLIN, E ;
DSOUZA, SW ;
BIANCHI, A .
ARCHIVES OF DISEASE IN CHILDHOOD, 1992, 67 (11) :1353-1356
[9]   The newborn exstrophy bladder inadequate for primary closure: Evaluation, management and outcome [J].
Dodson, JL ;
Surer, I ;
Baker, LA ;
Jeffs, RD ;
Gearhart, JP .
JOURNAL OF UROLOGY, 2001, 165 (05) :1656-1659
[10]   The influence of delay in closure of the abdominal wall on outcome in gastroschisis [J].
Driver, CP ;
Bowen, J ;
Doig, CM ;
Bianchi, A ;
Dickson, AP ;
Bruce, J .
PEDIATRIC SURGERY INTERNATIONAL, 2001, 17 (01) :32-34