The failure of epigenetic combination therapy for cancer and what it might be telling us about DNA methylation inhibitors

被引:8
|
作者
Yang, Allen S. [1 ]
Yang, Brandon J. [2 ]
机构
[1] Spectrum Pharmaceut, Irvine, CA 92618 USA
[2] Albert Einstein Acad, Santa Clarita, CA 91355 USA
关键词
cancer; DNA methylation inhibitors; epigenetic therapy; histone deacetylase inhibitors; ACUTE MYELOID-LEUKEMIA; LOW-DOSE DECITABINE; MYELODYSPLASTIC SYNDROMES; HYPOMETHYLATING AGENTS; DNMT3A MUTATIONS; VALPROIC ACID; AZACITIDINE; TRIAL;
D O I
10.2217/epi.15.94
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:9 / 12
页数:4
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