Assessment of health-related quality-of-life in patients with chronic Rhinosinusitis - Validation of the German Sino-Nasal Outcome Test-22 (German-SNOT-22)

被引：22
作者：
Riedl, D. [1 ]
Dejaco, D. [2 ]
Steinbichler, T. B. [2 ]
Innerhofer, V. [2 ]
Gottfried, T. [2 ]
Bektic-Tadic, L. [2 ]
Giotakis, A. I. [2 ]
Rumpold, G. [1 ]
Riechelmann, H. [2 ]
机构：
[1] Med Univ Innsbruck, Dept Med Psychol, Schopfstr 23a, A-6020 Innsbruck, Tyrol, Austria
[2] Med Univ Innsbruck, Dept Otorhinolaryngol Head & Neck Surg, Anichstr 35, A-6020 Innsbruck, Tyrol, Austria
来源：
JOURNAL OF PSYCHOSOMATIC RESEARCH | 2021年 / 140卷
关键词：
Paranasal sinus diseases; Sinusitis; Health-related-quality-of-life; Patient reported outcome measures; Sino-Nasal-Outcome-Test-22; Validation-study; CROSS-CULTURAL ADAPTATION; TEST (SNOT)-22; CLINIMETRIC VALIDITY; TRANSLATION; SNOT-22; EPIDEMIOLOGY; VERSION;
D O I：
10.1016/j.jpsychores.2020.110316
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Purpose: The Sino-Nasal-Outcome-Test-22 (SNOT-22) represents the reference questionnaire to assess symptoms, health-related quality-of-life (HRQOL) and treatment-response in patients with chronic rhinosinusitis (CRS). The SNOT-22 has been validated for various languages, yet no validation is available for the German version. Thus, we provide a validation of the SNOT-22 for German. Methods: In this prospective observational study 139 CRS-patients and 36 control-participants were included. CRS-patients completed the German-SNOT-22 before treatment (T0) and four (T1), twelve (T2) and 48 weeks after inclusion (T3). At T0, Mackay-Naclerio-, Lund-Mackay- and Brief-Symptom-Inventory-18 (BSI-18) scores were collected as external reference for the German-SNOT-22 and its subscales. At T1, T2, and T3 health-transition-items (HTIs) were raised to explore responsivity. Control-participants completed the German-SNOT-22 at T0. Reliability (internal consistency, item-total correlation), validity (concurrent validity, discriminatory validity) and responsiveness (distribution- and anchor-based) were explored for the German-SNOT-22. Results: At T0, the mean German-SNOT-22 total-score for CRS patients was 38.0 (+/- 20.9) and responded to treatment (T1 = 26.3 +/- 19.1; T2 = 25.8 +/- 20.6; T3 = 20.5 +/- 16.3). For control-participants, the mean total-score at T0 was 15.1 (+/- 10.9). The German-SNOT-22 was reliable (excellent internal consistency alpha = 0.93; good overall item-total correlations r = 0.39-0.85), valid (significant correlations between Mackay-Naclerio-, Lund-Mackay- and BSI-18 scores, all r > 0.39, p < 0.01) and responsive (significant correlations between HTIs and mean change in German-SNOT-22 total-score F = 9.57, p < 0.001). Conclusion: The German-SNOT-22 validated here matches the original SNOT-22. It is a reliable, valid and responsive questionnaire to assess symptoms, HRQOL and treatment-response in CRS-patients. Good psychometric properties were observed.
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页数：8
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