rac-2-(2-Amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-2-hydroxyindane-1,3-dione

被引：2

作者：

Penthala, Narsimha Reddy ^{[1
]}

Reddy, Thirupathi Yerram Reddy ^{[1
]}

Parkin, Sean ^{[2
]}

Crooks, Peter A. ^{[1
]}

机构：

[1] Univ Kentucky, Coll Pharm, Dept Pharmaceut Sci, Lexington, KY 40536 USA

[2] Univ Kentucky, Dept Chem, Lexington, KY 40506 USA

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2009年 / 65卷

关键词：

D O I：

10.1107/S1600536809025574

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

In the crystal of the title compound, C12H8N2O4S, molecules are linked into chains by a series of intermolecular O-H center dot center dot center dot O, N-H center dot center dot center dot O and N-H center dot center dot center dot N hydrogen bonds. The ninhydrin and aminothiazolidine units make a dihedral angle of 66.41 (3)degrees. The crystal structure indicates the presence of equimolar R and S enantiomers in the crystal lattice, due to the presence of a chiral centre in the title compound.

引用

页码：O1877 / U3143

页数：10

共 7 条

[1] 2-Acetonyl-2-hydroxyindan-1,3-dione
Fun, Hoong-Kun
Quah, Ching Kheng
Parveen, Mehtab
Ghalib, Raza Murad
Mehdi, Sayed Hasan
[J]. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O1209 - U1203
[2] CRYSTAL STRUCTURE OF NINHYDRIN
MEDRUD, RC
[J]. ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL CRYSTALLOGRAPHY AND CRYSTAL CHEMISTRY, 1969, B 25 : 213 - &
[3] *NON BV, 1998, COLLECT DENZO
[4] Processing of X-ray diffraction data collected in oscillation mode
Otwinowski, Z
Minor, W
[J]. MACROMOLECULAR CRYSTALLOGRAPHY, PT A, 1997, 276 : 307 - 326
[5] Sekhar KR, 2003, CANCER RES, V63, P5636
[6] A short history of SHELX
Sheldrick, George M.
[J]. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2008, 64 : 112 - 122
[7] Novel substituted (Z)-2-(N-benzylindol-3-ylmethylene)-quinuclidin-3-one and (Z)-(±)-2-(N-benzylindol-3-ylmethylene)-quinuclidin-3-ol derivatives as potent thermal sensitizing agents
Sonar, Vijayakumar N.
Reddy, Y. Thirupathi
Sekhar, Konjeti R.
Sasi, Soumya
Freeman, Michael L.
Crooks, Peter A.
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (24) : 6821 - 6824

← 1 →