HIV incidence among injection drug users in New York City, 1992-1997: Evidence for a declining epidemic

被引:154
作者
Des Jarlais, DC
Marmor, M
Friedmann, P
Titus, S
Aviles, E
Deren, S
Torian, L
Glebatis, D
Murrill, C
Monterroso, E
Friedman, SR
机构
[1] Beth Israel Deaconess Med Ctr, Inst Chem Dependency, New York, NY 10003 USA
[2] NYU, Sch Med, New York, NY USA
[3] Natl Dev & Res Inst Inc, New York, NY 10013 USA
[4] New York City Dept Hlth, New York, NY 10013 USA
[5] Ctr Dis Control & Prevent, Atlanta, GA USA
关键词
D O I
10.2105/AJPH.90.3.352
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objectives. We assessed recent (1992-1997) HIV incidence in the large HIV epidemic among injection drug users in New York City. Methods. Data were compiled from 10 separate studies (N=4979), including 6 cohort studies, 2 "repeat service user" studies, and 2 analyses of voluntary HIV testing and counseling services within drug treatment programs. Results. In the 10 studies, 52 seroconversions were found in 6344 person-years at risk. The observed incidence rates among the 10 studies were all within a narrow range, from 0 per 100 person-years at risk to 2.95 per 100 person-years at risk. In 9 of the 10 studies, the observed incidence rate was less than 2 per 100 person-years at risk. The weighted average incidence rate was 0.7 per 100 person-years at risk. Conclusions. The recent incidence rate in New York City is quite low for a high-seroprevalence population of injection drug users. The very large HIV epidemic among injection drug users in New York City appears to have entered a "declining phase," characterized by low incidence and declining prevalence. The data suggest that very large high-seroprevalence HIV epidemics may be "reversed.".
引用
收藏
页码:352 / 359
页数:8
相关论文
共 33 条
[1]  
ANDERSON R, 1997, UNAIDS M HIV PREV ST
[2]  
BATTEGAY M, 1998, 12 INT C AIDS JUN 28
[3]   Prevalence and incidence rate of HIV, hepatitis B and C among drug users on methadone maintenance treatment in Geneva between 1988 and 1995 [J].
Broers, B ;
Junet, C ;
Bourquin, M ;
Déglon, JJ ;
Perrin, L ;
Hirschel, E .
AIDS, 1998, 12 (15) :2059-2066
[4]   RESURGENT TUBERCULOSIS IN NEW-YORK-CITY - HUMAN-IMMUNODEFICIENCY-VIRUS, HOMELESSNESS, AND THE DECLINE OF TUBERCULOSIS-CONTROL PROGRAMS [J].
BRUDNEY, K ;
DOBKIN, J .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1991, 144 (04) :745-749
[5]   HIV prevention in developed countries [J].
Coates, TJ ;
Aggleton, P ;
Gutzwiller, F ;
DesJarlais, D ;
Kihara, M ;
Kippax, S ;
Schechter, M ;
vandenHoek, JAR .
LANCET, 1996, 348 (9035) :1143-1148
[6]   Risk behavior and HIV infection among new drug injectors in the era of AIDS in New York City [J].
Des Jarlais, DC ;
Friedman, SR ;
Perlis, T ;
Chapman, TF ;
Sotheran, JL ;
Paone, D ;
Monterroso, E ;
Neaigus, A .
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 1999, 20 (01) :67-72
[7]   HIV-1 INFECTION AMONG INTRAVENOUS DRUG-USERS IN MANHATTAN, NEW-YORK-CITY, FROM 1977 THROUGH 1987 [J].
DESJARLAIS, DC ;
FRIEDMAN, SR ;
NOVICK, DM ;
SOTHERAN, JL ;
THOMAS, P ;
YANCOVITZ, SR ;
MILDVAN, D ;
WEBER, J ;
KREEK, MJ ;
MASLANSKY, R ;
BARTELME, S ;
SPIRA, T ;
MARMOR, M .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1989, 261 (07) :1008-1012
[8]  
DESJARLAIS DC, 1997, IN PRESS RISK REDUCT
[9]   OPIATE DEPENDENCY AMONG THE SUBSCRIBERS OF A NEW-YORK AREA PRIVATE INSURANCE PLAN [J].
EISENHANDLER, J ;
DRUCKER, E .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1993, 269 (22) :2890-2891
[10]  
Fleiss JL, 1981, STAT METHODS RATES P