Reactions to and Desire for Prognostic Testing in Choroidal Melanoma Patients

被引:52
作者
Beran, Tammy M. [2 ,3 ,4 ]
McCannel, Tara A. [1 ,3 ,4 ,5 ]
Stanton, Annette L. [2 ,5 ,6 ]
Straatsma, Bradley R. [3 ,4 ,5 ]
Burgess, Barry L. [3 ,4 ]
机构
[1] Univ Calif Los Angeles, JSEI Ophthalmol, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Dept Ophthalmol, Los Angeles, CA 90095 USA
[4] Univ Calif Los Angeles, Jules Stein Eye Inst, Los Angeles, CA 90095 USA
[5] Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Los Angeles, CA 90095 USA
[6] Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90095 USA
关键词
Choroidal melanoma; Prognostic testing; Patient preferences; Cytogenetic testing; Psychological adjustment; Chromosome; 3; Monosomy; Disomy; NEEDLE-ASPIRATION BIOPSY; UVEAL MELANOMA; CANCER SUSCEPTIBILITY; HEALTH SURVEY; MONOSOMY; CHROMOSOME-3; CYTOGENETICS; IDENTIFICATION; ABNORMALITIES; MANAGEMENT;
D O I
10.1007/s10897-009-9223-2
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
To determine if choroidal melanoma patients want cytogenetic prognostic information. Ninety-nine choroidal melanoma patients completed a questionnaire regarding their opinions about receiving prognostic information. The perceived usefulness of prognostic information was evaluated in patients who had undergone cytogenetic testing. Depressive symptoms, quality of life, and interest in supportive counseling during test receipt were assessed. Ninety-seven percent of respondents reported that they would have wanted prognostic information at the time of their treatment and 98% of respondents reported that supportive counseling should be offered when prognostic information is given. Patients who had received a more favorable prognostic result were more likely to endorse the usefulness of cytogenetic testing than were patients who had received a less favorable prognostic result. Psychological status did not vary significantly as a function of cytogenetic test result. Prognostic information was important to patients with choroidal melanoma, even in the absence of prophylactic measures which might improve prognosis.
引用
收藏
页码:265 / 274
页数:10
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