Phlorotannins as radical scavengers from the extract of Sargassum ringgoldianum

被引：83

作者：

Nakai, Masaaki ^{[1
]}

Kageyama, Norihiko ^{[1
]}

Nakahara, Koichi ^{[1
]}

Miki, Wataru ^{[1
]}

机构：

[1] Suntory Ltd, Sunbury Res Ctr, Osaka 6188503, Japan

来源：

MARINE BIOTECHNOLOGY | 2006年 / 8卷 / 04期

关键词：

bifuhalol; phlorotannin; radical scavenger; Sargassum ringgoldianum;

D O I：

10.1007/s10126-005-6168-9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

To screen algal phlorotannins with antioxidative activities, 50% ethanol extracts of 25 Japanese marine algae were evaluated. Scavenging activity against superoxide anion radicals was frequently found with a high content of total phenolic compounds. Among these, the extract from the brown seaweed, Sargassum ringgoldianum, showed the strongest scavenging activity. The active fraction contained a mixture of high molecular weight polyphenols, phlorotannins that were found to be polymerized bifuhalol, as analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The scavenging activity of the fraction against superoxide anion radicals was estimated to be 1.0 mu g/ml (IC50), which were approximately five times stronger than that of catechin.

引用

页码：409 / 414

页数：6

共 33 条

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