3D hierarchical scaffolds enabled by a post-patternable, reconfigurable, and biocompatible 2D vitrimer film for tissue engineering applications

被引：7
|
作者：
Kim, Na Kyung [1 ,2 ]
Cha, Eun Jung [3 ]
Jung, Mungyo [1 ,2 ]
Kim, Jinseok [1 ,2 ]
Jeong, Gun-Jae [1 ,2 ]
Kim, Yong Seok [3 ]
Choi, Woo Jin [4 ]
Kim, Byung-Soo [1 ,2 ]
Kim, Dong-Gyun [3 ]
Lee, Jong-Chan [1 ,2 ]
机构：
[1] Seoul Natl Univ, Sch Chem & Biol Engn, 599 Gwanak Ro, Seoul 08826, South Korea
[2] Seoul Natl Univ, Inst Chem Proc, 599 Gwanak Ro, Seoul 08826, South Korea
[3] Korea Res Inst Chem Technol, Adv Mat Div, 141 Gajeong Ro, Daejeon 34114, South Korea
[4] Korea Res Inst Chem Technol, Chem Mat Solut Ctr, 141 Gajeong Ro, Daejeon 34114, South Korea
来源：
JOURNAL OF MATERIALS CHEMISTRY B | 2019年 / 7卷 / 21期
基金：
新加坡国家研究基金会;
关键词：
POLYMER; FABRICATION; STATE;
D O I：
10.1039/c9tb00221a
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
A mechanically tissue-like, biocompatible vitrimer film for tissue engineering scaffold applications is presented. 3D hierarchical scaffolds are prepared from the 2D vitrimer film via transesterificationinduced hot embossing patterning and additional reconfiguration processes. Microsized grooves patterned on the vitrimer surface are found to enhance C2C12 cell elongation and alignment for promoted muscle regeneration.
引用
收藏
页码：3341 / 3345
页数：5
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