CHARACTERISTICS OF CENTRAL SEROUS CHORIORETINOPATHY COMPLICATED BY FOCAL CHOROIDAL EXCAVATION

Purpose: To investigate the characteristics of central serous chorioretinopathy complicated by focal choroidal excavation (FCE) using fundus angiography and optical coherence tomography (OCT). Methods: A retrospective single-institution study. We reviewed the charts of 7 eyes of 7 patients (5 men, 2 women; mean age, 56.9 +/- 9.8 years) with central serous chorioretinopathy complicated by FCE using fundus angiography and OCT. Results: In six of the seven eyes, the points of leakage were at the edge of FCE on OCT. All FCE lesions were hypofluorescent from early to late phase on indocyanine green angiography. All eyes had late-phase hyperfluorescence on indocyanine green angiography secondary to choroidal vascular hyperpermeability around the FCE lesion. Five fellow eyes also had choroidal vascular hyperpermeability. The mean subfoveal choroidal thicknesses by swept source high-penetration OCT were 377 mu m and 333 mu m in the fellow eyes, a difference that did not reach significance (P = 0.21). Conclusion: Fundus angiography and OCT showed that choroidal circulatory disruption and atrophic retinal pigment epithelium at the FCE lesion might be related to central serous chorioretinopathy complicated by FCE.