Functionalization of chitosan by click chemistry

被引：8

作者：

Cheaburu-Yilmazi, Catalina Natalia ^{[1
,2
]}

Karavana, Sinem Yaprak ^{[2
]}

Yilmaz, Onur ^{[3
]}

机构：

[1] Petru Poni Inst Macromol Chem, Dept Phys Chem Polymers, Iasi, Romania

[2] Ege Univ, Dept Pharmaceut Technol, Fac Pharm, Izmir, Turkey

[3] Ege Univ, Dept Leather Engn, Fac Engn, TR-35100 Izmir, Turkey

来源：

RECENT ADVANCES ON ENVIRONMENT, CHEMICAL ENGINEERING AND MATERIALS | 2017年 / 1918卷

关键词：

D O I：

10.1063/1.5018504

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Chitosan modification represents a challenge nowadays. The variety of compounds which can be obtained with various architectures and different functionalities made it attractive to be used in fields like pharmacy and material science. Presents study deals with the chemical modification of chitosan by using click chemistry technique. The study adopted the approach of clicking azidated chitosan with a synthesized alkyne terminated polymer i.e. poly N isopropylacrylamide with thennoresponsive properties. Structures were confirmed by the FT-IR and HNMR spectra. Thermal characterization was performed showing different thermal behaviour with the chemical modification. The final synthesized graft copolymer can play important role within pharmaceutical formulations carrying drugs for topical or oral treatments.

引用

页数：6

共 8 条

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