Developments in ion mobility spectrometry-mass spectrometry

被引：125

作者：

Collins, DC

Lee, ML ^{[1
]}

机构：

[1] Weber State Univ, Dept Criminal Justice, Ogden, UT 84408 USA

[2] Brigham Young Univ, Dept Chem & Biochem, Provo, UT 84602 USA

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2002年 / 372卷 / 01期

关键词：

ion mobility spectrometry; mass spectrometry; gas-phase electrophoresis; plasma chromatography;

D O I：

10.1007/s00216-001-1195-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Ion mobility spectrometry (IMS) has been used for over 30 years as a sensitive detector of organic compounds. The following is a brief review of IMS and its principles with an emphasis on its usage when coupled to mass spectrometry, Since its inception, IMS has been interfaced with quadrupole, time-of-flight, and Fourier-transform ion cyclotron resonance mass spectrometry. These hybrid instruments have been employed for the analysis of a variety of target analytes, including biomolecules, explosives. chemical warfare degradation products, and illicit drugs.

引用

页码：66 / 73

页数：8

共 67 条

[1] Separation and identification of some chemical warfare degradation products using electrospray high resolution ion mobility spectrometry with mass selected detection [J].