Prenylated stilbenes and flavonoids from the leaves of Cajanus cajan

被引:14
作者
Wu Gui-Yun [1 ,2 ]
Zhang Xiao [1 ,2 ]
Guo Xue-Ying [2 ]
Huo Lu-Qiong [2 ]
Liu Hong-Xin [2 ,3 ]
Shen Xiao-Ling [1 ]
Qiu Sheng-Xiang [2 ]
Hu Ying-Jie [1 ]
Tan Hai-Bo [2 ]
机构
[1] Guangzhou Univ Chinese Med, Inst Trop Med, Lab Chinese Herbal Drug Discovery, Guangzhou 510405, Guangdong, Peoples R China
[2] Chinese Acad Sci, South China Bot Garden, Guangdong Prov Key Lab Appl Bot, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China
[3] Guangdong Inst Microbiol, Guangzhou 510070, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
Cajanus cajan; Stilbenes; Flavonoids; Leguminosae; IN-VITRO; L; RESISTANCE; EXTRACTS;
D O I
10.1016/S1875-5364(19)30044-5
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Three new prenylated stilbenes, named as cajanusins A-C (1-3), and one new natural product cajanusin D (4), along with six known derivatives (5-10) were isolated from the leaves of Cajanus cajan. Their structures were fully elucidated by means of extensive spectroscopic methods and comparison with data in the reported literatures. The new compounds of 1 and 2 were evaluated for in vitro cytotoxic activities against a panel of human cancer cell lines.
引用
收藏
页码:381 / 386
页数:6
相关论文
共 29 条
  • [1] Aiyeloja AA, 2006, ED RES REV, V128, P16
  • [2] Ajaiyeoba E O, 2013, J Parasitol Res, V2013, P703781, DOI 10.1155/2013/703781
  • [3] The composition of pigeon peas (Cajanus cajan (L.) Millsp.) grown in Botswana
    Amarteifio, JO
    Munthali, DC
    Karikari, SK
    Morake, TK
    [J]. PLANT FOODS FOR HUMAN NUTRITION, 2002, 57 (02) : 173 - 177
  • [4] Borges AB, 2005, J BRAZIL CHEM SOC, V16, P1078
  • [5] A Halogen-Containing Stilbene Derivative from the Leaves of Cajanus cajan that Induces Osteogenic Differentiation of Human Mesenchymal Stem Cells
    Cai, Jia-Zhong
    Tang, Rong
    Ye, Gui-Fu
    Qiu, Sheng-Xiang
    Zhang, Nen-Ling
    Hu, Ying-Jie
    Shen, Xiao-Ling
    [J]. MOLECULES, 2015, 20 (06) : 10839 - 10847
  • [6] First total synthesis of natural products cajanolactone A and cajanonic acid A
    Chen, Wen-Zhang
    Fan, Ling-Ling
    Xiao, Hai-Tao
    Zhou, Ying
    Xiao, Wan
    Wang, Jian-Ta
    Tang, Lei
    [J]. CHINESE CHEMICAL LETTERS, 2014, 25 (05) : 749 - 751
  • [7] Ghosh A, 2006, J BIOCHEM MOL BIOL, V39, P197
  • [8] Medicinal plants of India with anti-diabetic potential
    Grover, JK
    Yadav, S
    Vats, V
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 2002, 81 (01) : 81 - 100
  • [9] Total synthesis of cajanine and its antiproliferative activity against human hepatoma cells
    Ji, Xing-yue
    Xue, Si-tu
    Zheng, Guang-hui
    Han, Yan-xing
    Liu, Zong-ying
    Jiang, Jian-dong
    Li, Zhuo-rong
    [J]. ACTA PHARMACEUTICA SINICA B, 2011, 1 (02) : 93 - 99
  • [10] Chemical constituents isolated from the Mongolian medicinal plant Sophora alopecuroides L. and their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages
    Kwon, Jaeyoung
    Basnet, Sunita
    Lee, Jin Woo
    Seo, Eun-Kyoung
    Tsevegsuren, Nanzad
    Hwang, Bang Yeon
    Lee, Dongho
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 25 (16) : 3314 - 3318