Factitious Biochemical Measurements Resulting From Hematologic Conditions

被引:46
作者
Dalal, Bakul I. [1 ]
Brigden, Malcolm L. [2 ]
机构
[1] Vancouver Gen Hosp, Div Hematopathol, Vancouver, BC V5Z 4E3, Canada
[2] Saskatoon Clin, Saskatchewan Canc Agcy, Saskatoon, SK, Canada
关键词
Artifact; Factitious; Hyperkalemia; Myeloma; Paraprotein; C-REACTIVE PROTEIN; BLOOD-GAS ANALYSIS; PARAPROTEIN INTERFERENCE; HEREDITARY STOMATOCYTOSES; MEMBRANE-PERMEABILITY; HEMOGLOBIN-VARIANTS; INORGANIC-PHOSPHATE; SERUM; PSEUDOHYPERKALEMIA; PATIENT;
D O I
10.1309/AJCPY9RP5QYTYFWC
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Factitious laboratory results often lead to unnecessary testing or treatment. This brief review of factitious biochemical results (lite to preexisting hematologic conditions focuses on the mechanisms underlying the factitious results and suggests ways to prevent them. An observant pathologist identifies these errors, intervenes in a timely fashion, investigates the sources of error diligently, and institutes measures to prevent their recurrence.
引用
收藏
页码:195 / 204
页数:10
相关论文
共 91 条
  • [1] ALEXANDER NM, 1980, CLIN CHIM ACTA, V100, P301, DOI 10.1016/0009-8981(80)90279-X
  • [2] ASTLES JR, 1995, ARCH PATHOL LAB MED, V119, P713
  • [3] BAYNES KCR, 2001, PRACTICAL DIABETES I, V18, P103
  • [4] Clinically significant pseudohyponatremia
    Bern, M
    [J]. AMERICAN JOURNAL OF HEMATOLOGY, 2006, 81 (07) : 558 - 559
  • [5] Hemoglobin Gorwihl [α2β25(A2)Pro→Ala], an electrophoretically silent variant with impaired glycation
    Bissé, E
    Schauber, C
    Zorn, N
    Epting, T
    Eigel, A
    Van Dorsselaer, A
    Wieland, H
    Kister, J
    Kiger, L
    [J]. CLINICAL CHEMISTRY, 2003, 49 (01) : 137 - 143
  • [6] Bonini P, 2002, CLIN CHEM, V48, P691
  • [7] CHARACTERISTICS OF MONOCLONAL IMMUNOGLOBULINS THAT INTERFERE WITH SERUM INORGANIC-PHOSPHATE MEASUREMENT
    BOWLES, SA
    TAIT, RC
    JEFFERSON, SG
    GILLEECE, MH
    HAENEY, MR
    [J]. ANNALS OF CLINICAL BIOCHEMISTRY, 1994, 31 : 249 - 254
  • [8] Morphologic abnormalities, pseudosyndromes, and spurious test results
    Brigden, ML
    Dalal, BI
    [J]. LABORATORY MEDICINE, 1999, 30 (06) : 397 - 405
  • [9] Cell counter-related abnormalities
    Brigden, ML
    Dalal, BI
    [J]. LABORATORY MEDICINE, 1999, 30 (05) : 325 - 334
  • [10] Bry L, 2001, CLIN CHEM, V47, P153