Targeting DNA-repair deficiency in mouse models for BRCA-associated breast cancer

被引：0

作者：

Jonkers, J. ^{[1
]}

机构：

[1] Netherlands Canc Inst, Amsterdam, Netherlands

来源：

EJC SUPPLEMENTS | 2009年 / 7卷 / 02期

关键词：

MAMMARY-TUMORS; RESISTANCE;

D O I：

10.1016/S1359-6349(09)70282-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：81 / 81

页数：1

共 7 条

[1] Resistance to therapy caused by intragenic deletion in BRCA2 [J].

Edwards, Stacey L. ;

Brough, Rachel ;

Lord, Christopher J. ;

Natrajan, Rachael ;

Vatcheva, Radost ;

Levine, Douglas A. ;

Boyd, Jeff ;

Reis-Filho, Jorge S. ;

Ashworth, Alan .

NATURE, 2008, 451 (7182) :1111-U8

[2] Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer [J].

Jonkers, J ;

Meuwissen, R ;

van der Gulden, H ;

Peterse, H ;

van der Valk, M ;

Berns, A .

NATURE GENETICS, 2001, 29 (04) :418-425

[3] Conditional mouse models of sporadic cancer [J].

Jonkers, J ;

Berns, A .

NATURE REVIEWS CANCER, 2002, 2 (04) :251-265

[4] Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer [J].

Liu, Xiaoling ;

Holstege, Henne ;

van der Gulden, Hanneke ;

Treur-Mulder, Marcelle ;

Zevenhoven, John ;

Velds, Arno ;

Kerkhoven, Ron M. ;

van Vliet, Martin H. ;

Wessels, Lodewyk F. A. ;

Peterse, Johannes L. ;

Berns, Anton ;

Jonkers, Jos .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (29) :12111-12116

[5] High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs [J].

Rottenberg, Sven ;

Jaspers, Janneke E. ;

Kersbergen, Ariena ;

van der Burg, Eline ;

Nygren, Anders O. H. ;

Zander, Serge A. L. ;

Derksen, Patrick W. B. ;

de Bruin, Michiel ;

Zevenhoven, John ;

Lau, Alan ;

Boulter, Robert ;

Cranston, Aaron ;

O'Connor, Mark J. ;

Martin, Niall M. B. ;

Borst, Piet ;

Jonkers, Jos .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (44) :17079-17084

[6] Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer [J].

Rottenberg, Sven ;

Nygren, Anders O. H. ;

Pajic, Marina ;

van Leeuwen, Fijs W. B. ;

van der Heijden, Ingrid ;

van de Wetering, Koen ;

Liu, Xiaoling ;

Visser, Karin E. Cle ;

Gilhuijs, Kenneth G. ;

Van Tellingen, Olaf ;

Schouten, Jan P. ;

Jonkers, Jos ;

Borst, Piet .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (29) :12117-12122

[7] Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers [J].

Sakai, Wataru ;

Swisher, Elizabeth M. ;

Karlan, Beth Y. ;

Agarwal, Mukesh K. ;

Higgins, Jake ;

Friedman, Cynthia ;

Villegas, Emily ;

Jacquemont, Celine ;

Farrugia, Daniel J. ;

Couch, Fergus J. ;

Urban, Nicole ;

Taniguchi, Toshiyasu .

NATURE, 2008, 451 (7182) :1116-U9

← 1 →