Naphto-Γ-pyrones from the marine-derived fungus Aspergillus foetidus

被引:7
作者
Antonov, Alexander S. [1 ]
Leshchenko, Elena V. [1 ,2 ]
Zhuravleva, Olesya I. [1 ,2 ]
Dyshlovoy, Sergey A. [1 ,2 ,3 ]
von Amsberg, Gunhild [3 ]
Popov, Roman S. [1 ]
Denisenko, Vladimir A. [1 ]
Kirichuk, Natalya N. [1 ]
Afiyatullov, Shamil Sh. [1 ]
机构
[1] GB Elyakov Pacific Inst Bioorgan Chem, Vladivostok, Russia
[2] Far Eastern Fed Univ, Vladivostok, Russia
[3] Univ Med Ctr Hamburg Eppendorf, Hubertus Wald Tumorzentrum, Dept Oncol Hematol & Bone Marrow Transplantat, Sect Pneumol, Humburg, Germany
关键词
Aspergillus foetidus; marine-derived fungus; naphto-γ -pyrones; secondary metabolites; NMR; cytotoxicity; colony formation;
D O I
10.1080/14786419.2019.1610954
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Nine naphto-gamma-pyrones rubrofusarine B (1), TMC 256 A1 (2), fansecinones A (3) and B (4), aurasperones A (5), B (6) and F (7), dianhydro-aurasperone C (8) and asperpyrone B (9) were isolated from the marine-derived fungus Aspergillus foetidus KMM 4694. Their structures were established based on spectroscopic methods. The effect of the substances on viability and colony formation of human drug-resistant prostate cancer 22Rv1 cell was evaluated.
引用
收藏
页码:131 / 134
页数:4
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