Interpretation of substituent-induced 13C NMR chemical shifts of oxindoles

被引：3

作者：

Kapiller-Dezsofi, R ^{[1
]}

Volk, B ^{[1
]}

机构：

[1] EGIS Pharmaceut Ltd, Div Chem Res, H-1475 Budapest, Hungary

来源：

NEW JOURNAL OF CHEMISTRY | 2004年 / 28卷 / 10期

关键词：

D O I：

10.1039/b403034f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Based on the C-13 NMR chemical shifts of more than 300 oxindole derivatives, substituent-induced chemical shifts have been calculated for this family of compounds. These substituent effects have been compared to those of monosubstituted benzenes and the correlation with the Hammett sigma values and dual substituent parameters has also been tested. By means of these validated substituent effects, the C-13 NMR chemical shifts of the oxindole skeleton containing various substituents can be accurately predicted.

引用

页码：1214 / 1220

页数：7

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