Improvement in corrected QT dispersion by physical training and percutaneous transluminal coronary angioplasty in patients with recent myocardial infarction

The aim of the present study was to assess whether physical training and percutaneous transluminal coronary angioplasty (PTCA) improve the corrected QT (QTc) dispersion in patients with recent myocardial infarction (MI). Twenty-four patients with recent MI were allocated to one of 3 groups: training (n=8), PTCA (n=7) or controls (n=9). Physical training as well as PTCA decreased QTc dispersion, whereas QTc dispersion increased in the control group. Changes in QTc dispersion after physical training or PTCA were inversely correlated with exercise-induced ST depression at the baseline test. These observations suggest that physical training, as well as PTCA, could improve QTc dispersion and electrical instability in patients with recent MI, possibly due to improvement of myocardial ischemia.