Methadone intoxication in a child: Toxic encephalopathy?

被引:31
作者
Anselmo, Marisol
Rainho, Antonio Campos
Vale, Maria do Carmo
Estrada, Joao
Valente, Rosalina
Correia, Manuela
Vieira, Jose Pedro
Barata, Deolinda
机构
[1] Hosp Dona Estefania, Dept Neurol, P-1159045 Lisbon, Portugal
[2] Hosp Dona Estefania, Intens Care Unit, P-1159045 Lisbon, Portugal
[3] Hosp Santa Maria, Dept Neurosurg, Lisbon, Portugal
[4] Hosp Santa Maria, Intens Care Unit, Dept Pediat, Lisbon, Portugal
关键词
D O I
10.1177/08830738060210071101
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Methadone is used in the treatment of opioid addiction. Acute intoxication can lead to severe consequences and can even be lethal. In several case reports and small series, a presumably toxic leukoencephalopathy is described resulting from inhalation of heroin. We present the case of a 3-year-old boy who ingested methadone accidentally. In a coma with acute obstructive hydrocephalus;wing to massive cerebellar. edema and supratentorial lesions, he was successfully treated with methylprednisolone and cerebrospinal fluid external drainage. To our knowledge, this is the first report of an encephalopathy associated with synthetic opioid intoxication.
引用
收藏
页码:618 / 620
页数:3
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