An efficient synthesis of a class of novel N-alkyl-N-aryl-4-hydroxyl-1-methyl-2-oxo-1,2-dihydro-3-quinolinecarbothioamides

被引：7

作者：

Spears, GW ^{[1
]}

Tsuji, K ^{[1
]}

Tojo, T ^{[1
]}

Nishimura, H ^{[1
]}

Ogino, T ^{[1
]}

机构：

[1] Fujisawa Pharmaceut Co Ltd, Med Chem Res Labs, Yodogawa Ku, Osaka 5328514, Japan

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2002年 / 39卷 / 04期

关键词：

D O I：

10.1002/jhet.5570390427

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The novel title compounds have been prepared in high yield by an optimized amide coupling followed by a Dieckmann cyclization. Additionally, this new route is amenable to preparative scale synthesis.

引用

页码：799 / 804

页数：6

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