Deleting IL-12 reduces lupus nephritis in MRL-Faslpr mice by decreasing intrarenal INF-γ secreting T cells.

被引:0
|
作者
Kikawada, E [1 ]
Vinay, DS [1 ]
Kelley, VR [1 ]
机构
[1] Brigham & Womens Hosp, Boston, MA 02115 USA
关键词
D O I
暂无
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:55A / 55A
页数:1
相关论文
共 11 条
  • [1] IL-12 deficiency in MRL-Faslpr mice delays nephritis and intrarenal IFN-γ expression, and diminishes systemic pathology
    Kikawada, E
    Lenda, DM
    Kelley, VR
    JOURNAL OF IMMUNOLOGY, 2003, 170 (07): : 3915 - 3925
  • [2] IL-34-Dependent Intrarenal and Systemic Mechanisms Promote Lupus Nephritis in MRL-Faslpr Mice
    Wada, Yukihiro
    Gonzalez-Sanchez, Hilda M.
    Weinmann-Menke, Julia
    Iwata, Yasunori
    Ajay, Amrendra K.
    Meineck, Myriam
    Kelley, Vicki R.
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2019, 30 (02): : 244 - 259
  • [3] IL-18 induced IL-12p40-independent of a lupus nephritis in MRL-Faslpr mice
    Menke, J.
    Rubin, Kelley V.
    Faust, J.
    Relle, M.
    Galle, P. R.
    Wandel, E.
    Schwarting, A.
    MEDIZINISCHE KLINIK, 2006, 101 (04) : A103 - A103
  • [4] IL-12 drives IFN-γ-dependent autoimmune kidney disease in MRL-Faslpr mice
    Schwarting, A
    Tesch, G
    Kinoshita, K
    Maron, R
    Weiner, HL
    Kelley, VR
    JOURNAL OF IMMUNOLOGY, 1999, 163 (12): : 6884 - 6891
  • [5] Intra-renal IL-18 triggers systemic lupus, while caspase-1 inhibition ameliorates IL-18 mediated nephritis in MRL-Faslpr mice
    Menke, J.
    Relle, M.
    Maar, B.
    Schwarting, A.
    ZEITSCHRIFT FUR RHEUMATOLOGIE, 2013, 72 : 142 - 142
  • [6] Interleukin 6 (IL-6) Deficiency Delays Lupus Nephritis in MRL-Faslpr Mice: The IL-6 Pathway as a New Therapeutic Target in Treatment of Autoimmune Kidney Disease in Systemic Lupus Erythematosus
    Cash, Hannes
    Relle, Manfred
    Menke, Julia
    Brochhausen, Christoph
    Jones, Simon A.
    Topley, Nicholas
    Galle, Peter R.
    Schwarting, Andreas
    JOURNAL OF RHEUMATOLOGY, 2010, 37 (01) : 60 - 70
  • [7] Intra-renal IL-18 Triggers Systemic Lupus, while Caspase-1 Inhibition Ameliorates IL-18 Mediated Nephritis in MRL-Faslpr mice.
    Menke, J.
    Schmitt, S.
    Maar, B.
    Schwarting, A.
    INTERNIST, 2013, 54 : 8 - 8
  • [8] Intra-renal IL-18 Triggers Systemic Lupus, while Caspase-1 Inhibition Ameliorates IL-18 Mediated Nephritis in MRL-Faslpr mice.
    Menke, J.
    Schmitt, S.
    Maar, B.
    Schwarting, A.
    INTERNIST, 2013, 54 (06): : 744 - 744
  • [9] γδT Cells Positively Regulate Contact Sensitivity (CS) Reaction via Modulation of INF-γ, IL-12 and TNF-α Production
    Strzepa, Anna
    Majewska-Szczepanik, Monika
    Szczepanik, Marian
    FOLIA BIOLOGICA-KRAKOW, 2013, 61 (3-4): : 205 - 210
  • [10] IL-12 enhances lymphoaccumulation by suppressing cell death of T cells in MRL-lpr/lpr mice
    Xu, HP
    Kurihara, H
    Ito, T
    Nakajima, S
    Hagiwara, E
    Yamanokuchi, H
    Asari, A
    JOURNAL OF AUTOIMMUNITY, 2001, 16 (02) : 87 - 95