California ground squirrel (Spermophilus beecheyi) blood sera inhibits crotalid venom proteolytic activity

被引：26

作者：

Biardi, JE

Coss, RG ^{[1
]}

Smith, DG

机构：

[1] Univ Calif Davis, Dept Psychol, Davis, CA 95616 USA

[2] Univ Calif Davis, Grad Grp Ecol, Davis, CA 95616 USA

[3] Univ Calif Davis, Dept Anthropol, Davis, CA 95616 USA

来源：

TOXICON | 2000年 / 38卷 / 05期

关键词：

D O I：

10.1016/S0041-0101(99)00179-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Some California ground squirrels (Spermophilus beecheyi) show limited necrosis following envenomation by northern Pacific rattlesnakes (Crotalus viridis oreganus). This study demonstrates that S. beecheyi blood sera inhibits venom proteases. Sera from rattlesnake-abundant habitats inhibited C. v. oreganus venom more effectively than venom from two allopatric rattlesnake species, C. v. viridis and C, atrox, suggesting evolutionary specialization. The pattern of inhibition among squirrel populations corresponds best with history of rattlesnake predation, in contrast to current rattlesnake density. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：713 / 721

页数：9

共 25 条

[1] Black C.C., 1963, B MUS COMP ZOOL HARV, V130, P113
[2] OPOSSUM SERUM ALPHA-1-PROTEINASE INHIBITOR - PURIFICATION, LINEAR SEQUENCE, AND RESISTANCE TO INACTIVATION BY RATTLESNAKE VENOM METALLOPROTEINASES
CATANESE, JJ
KRESS, LF
[J]. BIOCHEMISTRY, 1993, 32 (02) : 509 - 515
[3] DEVELOPMENT OF ANTISNAKE DEFENSES IN CALIFORNIA GROUND-SQUIRRELS (SPERMOPHILUS-BEECHEYI) - .2. MICROEVOLUTIONARY EFFECTS OF RELAXED SELECTION FROM RATTLESNAKES
COSS, RG
GUSE, KL
PORAN, NS
SMITH, DG
[J]. BEHAVIOUR, 1993, 124 : 137 - 164
[4] Coss RG, 1999, GEOGRAPHIC VARIATION IN BEHAVIOR, P180
[5] Coss Richard G., 1995, Perspectives in Ethology, V11, P83
[6] NATURAL ANTI-SNAKE VENOM PROTEINS
DOMONT, GB
PERALES, J
MOUSSATCHE, H
[J]. TOXICON, 1991, 29 (10) : 1183 - 1194
[7] Edwards DR, 1996, INT J OBESITY, V20, pS9
[8] STUDY OF SNAKE POPULATIONS IN CENTRAL CALIFORNIA
FITCH, HS
[J]. AMERICAN MIDLAND NATURALIST, 1949, 41 (03) : 513 - 579
[9] ECOLOGY OF THE CALIFORNIA GROUND SQUIRREL ON GRAZING LANDS
FITCH, HS
[J]. AMERICAN MIDLAND NATURALIST, 1948, 39 (03) : 513 - 596
[10] HOLMAN JA, 1979, PUBL MUS MICH STATE, V1, P203

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