Making or breaking the heart: From lineage determination to morphogenesis

被引:462
作者
Srivastava, Deepak
机构
[1] Univ Calif San Francisco, Gladstone Inst Cardiovasc Dis, San Francisco, CA 94158 USA
[2] Univ Calif San Francisco, Dept Pediat, San Francisco, CA 94158 USA
[3] Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94158 USA
关键词
D O I
10.1016/j.cell.2006.09.003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The cues governing cardiac cell-fate decisions, cardiac differentiation, and three-dimensional morphogenesis are rapidly being elucidated. Several themes are emerging that are relevant for childhood and adult heart disease and the growing field of stem cell biology. This review will consider our current understanding of cardiac cell-fate determination and cardiogenesis - largely derived from developmental studies in model organisms and human genetic approaches - and examine future implications for diagnosis, prevention, and treatment of heart disease in the young and old.
引用
收藏
页码:1037 / 1048
页数:12
相关论文
共 105 条
[91]  
Tanaka M, 1999, DEVELOPMENT, V126, P1269
[92]   Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome [J].
Tartaglia, M ;
Mehler, EL ;
Goldberg, R ;
Zampino, G ;
Brunner, HG ;
Kremer, H ;
van der Burgt, I ;
Crosby, AH ;
Ion, A ;
Jeffery, S ;
Kalidas, K ;
Patton, MA ;
Kucherlapati, RS ;
Gelb, BD .
NATURE GENETICS, 2001, 29 (04) :465-468
[93]   Heart disease and stroke statistics - 2006 update - A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee [J].
Thom, T ;
Haase, N ;
Rosamond, W ;
Howard, VJ ;
Rumsfeld, J ;
Manolio, T ;
Zheng, ZJ ;
Flegal, K ;
O'Donnell, C ;
Kittner, S ;
Lloyd-Jones, D ;
Goff, DC ;
Hong, YL ;
Adams, R ;
Friday, G ;
Furie, K ;
Gorelick, P ;
Kissela, B ;
Marler, J ;
Meigs, J ;
Roger, V ;
Sidney, S ;
Sorlie, P ;
Steinberger, J ;
Wasserthiel-Smoller, S ;
Wilson, M ;
Wolf, P .
CIRCULATION, 2006, 113 (06) :E85-E151
[94]  
Thomas T, 1998, DEVELOPMENT, V125, P3005
[95]   Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation [J].
Timmerman, LA ;
Grego-Bessa, J ;
Raya, A ;
Bertrán, E ;
Pérez-Pomares, JM ;
Díez, J ;
Aranda, S ;
Palomo, S ;
McCormick, F ;
Izpisúa-Belmonte, JC ;
de la Pompa, JL .
GENES & DEVELOPMENT, 2004, 18 (01) :99-115
[96]   Gain-of-function/Noonan syndrome SHP-2/Ptpn11 mutants enhance calcium oscillations and impair NFAT signaling [J].
Uhlén, P ;
Burch, PM ;
Zito, CL ;
Estrada, M ;
Ehrlich, BE ;
Bennett, AM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (07) :2160-2165
[97]   Foxh1 is essential for development of the anterior heart field [J].
von Both, I ;
Silvestri, C ;
Erdemir, T ;
Lickert, H ;
Walls, JR ;
Henkelman, RM ;
Rossant, J ;
Harvey, RP ;
Attisano, L ;
Wrana, JL .
DEVELOPMENTAL CELL, 2004, 7 (03) :331-345
[98]   Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor [J].
Wang, DZ ;
Chang, PS ;
Wang, ZG ;
Sutherland, L ;
Richardson, JA ;
Small, E ;
Krieg, PA ;
Olson, EN .
CELL, 2001, 105 (07) :851-862
[99]   Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract [J].
Xu, HS ;
Morishima, M ;
Wylie, JN ;
Schwartz, RJ ;
Bruneau, BG ;
Lindsay, EA ;
Baldini, A .
DEVELOPMENT, 2004, 131 (13) :3217-3227
[100]   Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer [J].
Yamagishi, H ;
Maeda, J ;
Hu, TH ;
McAnally, J ;
Conway, SJ ;
Kume, T ;
Meyers, EN ;
Yamagishi, C ;
Srivastava, D .
GENES & DEVELOPMENT, 2003, 17 (02) :269-281