Synthesis and Vanilloid Receptor (TRPV1) Activity of the Enantiomers of α-Fluorinated Capsaicin

被引：24
作者：
Winkler, Margit [1 ,2 ]
Moraux, Thomas [1 ,2 ]
Khairy, Hesham A. [3 ]
Scott, Roderick H. [3 ]
Slawin, Alexandra M. Z. [1 ,2 ]
O'Hagan, David [1 ,2 ]
机构：
[1] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland
[2] Univ St Andrews, Ctr Biomol Sci, St Andrews KY16 9ST, Fife, Scotland
[3] Univ Aberdeen, Inst Med Sci, Sch Med Sci, Aberdeen AB25 2ZD, Scotland
来源：
CHEMBIOCHEM | 2009年 / 10卷 / 05期
关键词：
capsaicin; fluorinated ligands; medicinal chemistry; organofluorine; stereoselective catalysis; C-F BOND; ANALGESIC AGENTS; AGONIST ACTIVITY; SENSORY NEURONS; ANALOGS; REGION; SENSITIVITY; CHEMISTRY; ALDEHYDES; AMIDES;
D O I：
10.1002/cbic.200800709
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：823 / 828
页数：6
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