Controllable preparation of graphene oxide/metal nanoparticle hybrids as surface-enhanced Raman scattering substrates for 6-mercaptopurine detection

被引：18
作者：
Fu, Wen Liang [1 ]
Zhen, Shu Jun [1 ]
Huang, Cheng Zhi [1 ,2 ]
机构：
[1] Southwest Univ, Coll Chem & Chem Engn, Minist Educ, Key Lab Luminescent & Real Time Analyt Chem, Chongqing 400715, Peoples R China
[2] Southwest Univ, Coll Pharmaceut Sci, Minist Educ, Key Lab Luminescent & Real Time Analyt Chem, Chongqing 400715, Peoples R China
来源：
RSC ADVANCES | 2014年 / 4卷 / 31期
基金：
中国国家自然科学基金;
关键词：
MALACHITE GREEN DETECTION; WALLED CARBON NANOTUBES; IN-SITU SERS; ULTRASENSITIVE DETECTION; LABEL-FREE; OXIDE; SPECTROSCOPY; CELLS; NANOCOMPOSITES; FABRICATION;
D O I：
10.1039/c4ra00658e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this contribution, a new simple and cost-effective strategy for the preparation of hybrids of graphene oxide (GO) and metal nanoparticles (MNPs) through the mediation of polyethyleneimine (PEI) molecules was reported. PEI molecules as cationic polymers could effectively attach onto the surface of GO for further negative MNP adsorption. By this process, gold and silver nanoparticles are assembled on GO with high efficiency. This method has also been successfully applied to the assembly of metal nanoparticles and carbon nanotubes (CNTs), indicating that this method is general. Furthermore, the asprepared graphene oxide/silver nanoparticle (GO/AgNP) hybrids have been used as perfect surface enhanced Raman scattering (SERS) substrates with an enhancement factor of 1.5 Chi 10(5) and successfully applied for the sensitive and selective detection of 6- mercaptopurine (6MP) in pharmaceutical tablets with satisfactory results.
引用
收藏
页码：16327 / 16332
页数：6
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