The first asymmetric syntheses of L-homocysteine and L-homocystine

被引：6

作者：

Adamczyk, M ^{[1
]}

Fishpaugh, JR ^{[1
]}

Thiruvazhi, M ^{[1
]}

机构：

[1] Abbott Labs, Dept Chem 9NM AP20, Div Diagnost, Abbott Pk, IL 60064 USA

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 21期

关键词：

D O I：

10.1016/S0957-4166(99)00453-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Asymmetric syntheses of L-homocysteine 1 and L-homocystine 2 are described. Alkylation of the carbanion derived from Schollkopf reagent 3 and ensuing hydrolyses gave S-triphenylmethyl-L-homocysteine 6, Removal of the triphenylmethyl group gave L-homocysteine 1 and subsequent oxidation provided L-homocystine 2. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：4151 / 4156

页数：6

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