Ferroptosis: the Good, the Bad and the Ugly

被引:34
作者
Aldrovandi, Maceler [1 ]
Conrad, Marcus [1 ,2 ]
机构
[1] Helmholtz Zentrum Munchen, Inst Metab & Cell Death, Ingolstadter Landstr 1, D-85764 Neuherberg, Germany
[2] Natl Res Med Univ, Expt Oncol Lab, Ostrovityanova 1, Moscow 117997, Russia
关键词
LIPIDS; PLASMALOGEN;
D O I
10.1038/s41422-020-00434-0
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Polyunsaturated ether phospholipids, previously thought to oppose propagation of lipid peroxidation, have been reported to promote the cells' susceptibility to ferroptotic cell death. A recent study by Zou and colleagues now sheds a new light on the importance of the peroxisome-ether phospholipid axis in modulating ferroptosis susceptibility and evasion.
引用
收藏
页码:1061 / 1062
页数:2
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