Increased CSF hypocretin-1 (orexin-A) in restless legs syndrome

被引：52
|
作者：
Allen, RP
Mignot, E
Ripley, B
Nishino, S
Earley, CJ
机构：
[1] Stanford Univ, Ctr Narcolepsy, Palo Alto, CA 94304 USA
[2] Stanford Univ, Sch Med, Dept Psychiat, Palo Alto, CA 94304 USA
[3] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21218 USA
来源：
NEUROLOGY | 2002年 / 59卷 / 04期
关键词：
D O I：
10.1212/WNL.59.4.639
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Hypocretin-1 levels were increased in evening CSF samples from subjects with restless legs syndrome, indicating altered hypocretin transmission in this sleep disorder. Increases in CSF hypocretin-1 levels were most striking in patients with early-onset restless legs syndrome.
引用
收藏
页码：639 / 641
页数：3
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