Older polytrauma: Mortality and complications

被引:39
作者
de Vries, Rob [1 ]
Reininga, Inge H. F. [1 ,2 ]
de Graaf, Max W. [1 ]
Heineman, Erik [3 ]
El Moumni, Mostafa [1 ]
Wendt, Klaus W. [1 ]
机构
[1] Univ Med Ctr Groningen, Dept Trauma Surg, POB BA13, NL-9700 VB Groningen, Netherlands
[2] Nothern Netherlands Trauma Registry, AZNN, Emergency Care Network Northern Netherlands, Groningen, Netherlands
[3] Univ Med Ctr Groningen, Dept Surg, Groningen, Netherlands
来源
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | 2019年 / 50卷 / 08期
关键词
Polytrauma; Elderly; Geriatric trauma; Mortality; Complications; Predisposing factors; ELDERLY TRAUMA PATIENTS; LEVEL-I TRAUMA; COMORBIDITY-POLYPHARMACY SCORE; MAJOR TRAUMA; AGE; IMPUTATION; EMERGENCY; INJURY; RISK;
D O I
10.1016/j.injury.2019.06.024
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Introduction: Older adults enduring a polytrauma have an increased mortality risk. Apart from age, the role of other predisposing factors on mortality are mainly described for the total polytrauma population. This study aimed to describe the mortality pattern of older polytrauma patients, its associated risk factors, and the role and etiology of in-hospital complications. Methods: An eight-year retrospective cohort was constructed from 380 polytrauma patients aged >= 65 in a Dutch level 1 trauma center and linked to the national trauma database (DTR). Demographics, injury characteristics, comorbidity, clinical characteristics, in-hospital mortality, mortality etiology and complications scored according to the Clavien-Dindo classification were analyzed. Primary outcome was the identification of risk factors associated with in-hospital mortality, followed by identification of in-hospital complications and their nature. Results: Overall in-hospital mortality was 36.3%, rising significantly with age. For patients aged >= 85 inhospital mortality was 60.8%. Polytrauma patients aged >= 75 showed a peak of late-onset deaths one week following trauma. Age, a Glasgow coma score <= 8, coagulopathy, acidosis, injury severity score and the presence of a large subdural hematoma were significant risk factors influencing in-hospital mortality. Respiratory failure was the most prevalent severe and fatal complication. The proportion of fatal complications grew significantly with age (p <0.01). Conclusions: Age is strongly associated with in-hospital mortality in polytraumatized elderly. Coagulopathy, acidosis, a low Glasgow coma score, presence of a large subdural hematoma and injury severity score were independently of age associated with an increased mortality. Patients older than 75 years showed a unique trimodal distribution of mortality with a late onset one week following the initial trauma. Elderly were more susceptible for fatal complications. Respiratory failure was the most prevalent severe and fatal complication. Aggressive monitoring and treatment of the pulmonary status is therefore of utmost importance. (C) 2019 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1440 / 1447
页数:8
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