Hysterectomy in case of low-risk gestational trophoblastic neoplasia

被引：0

作者：

Massardier, J. ^{[1
,2
,3
]}

Mathe, M. ^{[1
,2
]}

Bolze, P. -A. ^{[1
,2
]}

Hajri, T. ^{[1
,7
]}

Devouassoux-Shisheboran, M. ^{[1
,2
,6
]}

Schott, A. -M. ^{[1
,2
,7
]}

Lotz, J. -P. ^{[1
,8
]}

You, B. ^{[1
,2
,5
]}

Golfier, F. ^{[1
,2
,4
,9
]}

机构：

[1] CHLS, Hosp Civils Lyon, Ctr Francais Malad Trophoblast, F-69495 Pierre Benite, France

[2] Univ Lyon 1, F-69373 Lyon 08, France

[3] HFME, Hosp Civils Lyon, Serv Gynecol Obstet, F-69500 Bron, France

[4] CHLS, Hosp Civils Lyon, Serv Gynecol Obstet, F-69495 Pierre Benite, France

[5] CHLS, Hosp Civils Lyon, Serv Oncol Med, F-69495 Pierre Benite, France

[6] Hop Croix Rousse, Hosp Civils Lyon, Serv Anatomopathol, F-69004 Lyon, France

[7] Hosp Civils Lyon, F-69424 Lyon 03, France

[8] Univ Paris 06, Hop Tenon, AP HP, Serv Oncol Med & Therapie Cellulaire, F-75970 Paris 20, France

[9] Univ Lyon 1, EMR Ciblage Therapeut Oncol 3738, F-69373 Lyon 08, France

来源：

ONCOLOGIE | 2014年 / 16卷 / 06期

关键词：

Hysterectomy; Gestational trophoblastic neoplasia; Hydatidiform mole; HYDATIDIFORM MOLE; MANAGEMENT; DISEASE; WOMEN;

D O I：

10.1007/s10269-014-2401-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Single agent chemotherapy, most usually methotrexate, is the treatment for low-risk Gestational Trophoblastic Neoplasia (GTN). The role of hysterectomy is not clearly known in this situation. Complete hCG normalization after hysterectomy was evaluated in case of low-risk GTN, in the French Center for Trophoblastic Disease, Lyon, France, between 1999 and 2013. Forty-three patients out of the fifty-four included (80%) were cured by hysterectomy alone. No criteria were predictive of failure. Hysterectomy could be an option in certain cases of low-risk GTN, especially on patient's request.

引用

页码：285 / 290

页数：6

共 22 条

[1]

Alazzam M, 2008, J REPROD MED, V53, P519

[2] First-line chemotherapy in low-risk gestational trophoblastic neoplasia [J].

Alazzam, Mo'iad ;

Tidy, John ;

Hancock, Barry W. ;

Osborne, Raymond ;

Lawrie, Theresa A. .

COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2012, (07)

[3] Methotrexate for 2000 FIGO low-risk gestational trophoblastic neoplasia patients: efficacy and toxicity [J].

Chalouhi, Gihad Elias ;

Golfier, Francois ;

Soignon, Pauline ;

Massardier, Jerome ;

Guastalla, Jean-Paul ;

Trillet-Lenoir, Veronique ;

Schott, Anne-Marie ;

Raudrant, Daniel .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2009, 200 (06) :643.e1-643.e6

[4]

Clark RM, 2010, J REPROD MED, V55, P194

[5]

Deng L, 2013, COCHRANE DB SYST REV, V1

[6] The Role of Surgery in the Management of Gestational Trophoblastic Neoplasia [J].

Doll, Kemi M. ;

Soper, John T. .

OBSTETRICAL & GYNECOLOGICAL SURVEY, 2013, 68 (07) :533-542

[7]

Elias KM, 2012, J REPROD MED, V57, P254

[8]

Golfier F, 2000, J Gynecol Obstet Biol Reprod (Paris), V29, P538

[9] Management of gestational trophoblastic disease [J].

Golfier, F. ;

Massardier, J. ;

Guastalla, J. -P. ;

Trillet-Lenoir, V. ;

Frappart, L. ;

Mathian, B. ;

Hajri, T. ;

Schott, A. -M. ;

Raudrant, D. .

JOURNAL DE GYNECOLOGIE OBSTETRIQUE ET BIOLOGIE DE LA REPRODUCTION, 2010, 39 :F25-F32

[10]

Golfier F, 2007, AM J OBSTET GYNECOL, V196

← 1 2 3 →