Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

被引：17
作者：
Nouvel, Laurent X.
Kassa-Kelembho, Eric
Dos Vultos, Tiago
Zandanga, Germain
Rauzier, Jean
Lafoz, Carmen
Martin, Carlos
Blazquez, Jesus
Talarmin, Antoine
Gicquel, Brigitte
机构：
[1] Inst Pasteur, Unite Genet Mycobacterienne 1, F-75724 Paris 12, France
[2] Inst Pasteur, Bangui, Cent Afr Republ
[3] Univ Zaragoza, Zaragoza, Spain
[4] Ctr Nacl Biotecnol, Madrid, Spain
来源：
EMERGING INFECTIOUS DISEASES | 2006年 / 12卷 / 09期
关键词：
D O I：
10.3201/eid1209.060361
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene. However, strains had different rpoB mutations responsible for rifampin resistance. MDR strains in Bangui may emerge preferentially from a single, MDR-prone family.
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收藏
页码：1454 / 1456
页数：3
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