Methylprednisolone - acute spinal cord injury, benefits or risks?

被引：0
作者：
Tesiorowski, Maciej [1 ]
Potaczek, Tomasz [1 ]
Jasiewicz, Barbara [1 ]
Sapa, Jacek [2 ]
Zygmunt, Malgorzata [2 ]
机构：
[1] Uniwersytetu Jagiellonskiego, Katedra & Klin Ortopedii & Rehabil Zakopanem, Coll Med, PL-30688 Krakow, Poland
[2] Uniwersytetu Jagiellonskiego, Zaklad Wstepnych Badan Farmakol, Katedry Farmakodynamiki, Coll Med, PL-30688 Krakow, Poland
来源：
POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ | 2013年 / 67卷
关键词：
methylprednisolone; acute spinal cord injury; inflammatio; neuroprotection; HIGH-DOSE METHYLPREDNISOLONE; EFFICACY; STEROIDS; NALOXONE;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Methylprednisolone is a synthetic glucocorticoid with a potent and long-acting anti-inflammatory, antiallergic and immunosuppressant. Its mechanism of action of methylprednisolone is the result of many cellular changes. Methylprednisolone is used in many diseases, such as rheumatic diseases, autoimmune diseases, allergic, anaphylactic shock, asthma. Methylprednisolone was also used in patients with spinal cord injury, in order to minimize neurological damage. While in the above mentioned fields of medicine is undeniable role of methylprednisolone, whereas its use in the treatment of traumatic spinal cord injury within the last few years raises a lot of controversy, and in most cases, the side effects of its use outweigh the potential benefits.
引用
收藏
页码：601 / 609
页数：9
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