The current role of glycopeptides in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in not neutropenic adults: the viewpoint of a group of Italian experts

被引：1

作者：

Concia, Ercole ^{[1
]}

Viscoli, Claudio ^{[2
]}

Del Bono, Valerio ^{[2
]}

Giannella, Maddalena ^{[3
]}

Bassetti, Matteo ^{[4
]}

De Rosa, Giuseppe Francesco ^{[5
]}

Mangoni, Emanuele Durante ^{[6
]}

Esposito, Silvano ^{[7
]}

Giusti, Massimo ^{[8
]}

Grossi, Paolo ^{[9
]}

Menichetti, Francesco ^{[10
]}

Pea, Federico ^{[4
]}

Petrosillo, Nicola ^{[11
]}

Tumbarello, Mario ^{[12
]}

Stefani, Stefania ^{[13
]}

Venditti, Mario ^{[14
]}

Pierluigi, Viale ^{[3
]}

机构：

[1] Univ Verona, Dipartimento Diagnost & Sanita Pubbl, Sez Malattie Infett, Verona, Italy

[2] Univ Genoa, AOU IRCCS San Martino, Clin Malattie Infett, Genoa, Italy

[3] Univ Bologna, Osped St Orsola Malpighi, Dipartimento Sci Med & Chirurg, Settore Malattie Infett, Bologna, Italy

[4] AOU Santa Maria della Misericordia, Clin Malattie Infett Bassetti, Ist Farmacol Clin Pea, Udine, Italy

[5] Univ Torino, Dipartimento Sci Med, Malattie Infett, Turin, Italy

[6] Univ Campania Luigi Vanvitelli, Caserta, Italy

[7] Univ Salerno, Dipartimento Med Chirurg & Odontoiatria, Scuola Med Salernitana, Salerno, Italy

[8] AO San Giovanni Bosco, Reparto Med Interna A, Turin, Italy

[9] Univ Insubria, Dipartimento Med Interna Malattie Infett & Trop, Varese, Italy

[10] AOU Pisana, Unita Operat UO Malattie Infett, Pisa, Italy

[11] Ist Nazl Malattie Infett Lazzaro Spallanzani, UOC Infez Sistem & Immunodepresso, Rome, Italy

[12] Univ Cattolica Sacro Cuore, Fac Med & Chirurg, Clin Malattie Infett, Rome, Italy

[13] Univ Catania, Dipartimento Sci Biomed & Biotecnol, Catania, Italy

[14] Univ Roma La Sapienza, AO Policlin Umberto 1, Dipartimento Sanita Pubbl & Malattie Infett, Rome, Italy

来源：

JOURNAL OF CHEMOTHERAPY | 2018年 / 30卷 / 03期

关键词：

Glycopeptides; MRSA; Infections; MINIMUM INHIBITORY CONCENTRATION; ACUTE BACTERIAL-MENINGITIS; BLOOD-STREAM INFECTIONS; CEREBROSPINAL-FLUID; DISEASES-SOCIETY; REDUCED SUSCEPTIBILITY; DAPTOMYCIN RESISTANCE; NOSOCOMIAL PNEUMONIA; PRACTICE GUIDELINES; TEICOPLANIN USE;

D O I：

10.1080/1120009X.2017.1420610

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Staphylococcus aureus is still an important problem in clinical and therapeutic area, worldwide. In Italy, in recent years, methicillin resistance remained stable, yet considerably high, the percentage of strains of MRSA being around 40%. It was deemed interesting and timely to carry out a consensus conference using the RAND/UCLA method to collect the opinion of a group of experts in infectious diseases on the role of glycopeptides in the management of MRSA infections within several clinical scenarios and namely in pneumonia, bacteremia and endocarditis, joint replacement infections, skin and soft tissue infections, diabetic foot, abdominal infections and central nervous system infections. The scenarios proposed by the Scientific Committee have been validated by a group of experts in infectious diseases and then voted in three meetings of infectious disease specialists. The results obtained on each individual condition were analyzed and therapeutic recommendations on each of these were released.

引用

页码：157 / 171

页数：15

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