Novel polymorphisms in the upstream region of the human dopamine D4 receptor (DRD4) gene

被引：28

作者：

Mitsuyasu, H ^{[1
]}

Ozawa, H ^{[1
]}

Takeda, Y ^{[1
]}

Fukumaki, Y ^{[1
]}

机构：

[1] Kyushu Univ, Inst Genet Informat, Div Dis Genes, Higashi Ku, Fukuoka 8128582, Japan

来源：

JOURNAL OF HUMAN GENETICS | 1999年 / 44卷 / 06期

关键词：

dopamine D4 receptor gene; promoter; polymorphisms; RFLP;

D O I：

10.1007/s100380050191

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We found nine novel polymorphisms in the upstream region of the human dopamine D4 receptor (DRD4) gene of Japanese by direct sequencing. These polymorphisms are -809G > A, -768G > A, -616C > G, -603T > del, -602G > del, -600G > C, -376C > T, -291C > T, and -128G > T. One known polymorphism, -521C > T, was also recognized. Six of these sites were identified as restriction fragment length polymorphisms (RFLPs).

引用

页码：416 / 418

页数：3

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