CARDIOVASCULAR RISK IN PSORIATIC ARTHRITIS

被引：0

作者：

Badokin, V. V. ^{[1
]}

Yanysheva, A. V. ^{[1
]}

Alexandrova, E. N. ^{[2
]}

Mach, E. S. ^{[2
]}

Popkova, T. V. ^{[2
]}

机构：

[1] Russian Med Acad Postgrad Educ, Moscow, Russia

[2] Russian Acad Med Sci, State Inst Rheumatol, Moscow, Russia

来源：

TERAPEVTICHESKII ARKHIV | 2009年 / 81卷 / 06期

关键词：

psoriatic arthritis; atherosclerosis; dyslipidemia; inflammation; C-REACTIVE PROTEIN; SUBCLINICAL ATHEROSCLEROSIS; CAROTID ATHEROSCLEROSIS; RHEUMATOID-ARTHRITIS; METABOLIC SYNDROME; DISEASE; PREVALENCE; MORTALITY; PROFILE; DEATH;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim. To evaluate cardiovascular risk in psoriatic arthritis (PA). Material and methods. The examination covered 61 PA patients (52.9% females) aged 30-55 years and 45 controls without inflammatory and degeneratory diseases matched by gender, age and body mass. Standard cardiovascular risk factors were analysed. C-reactive protein was measured with a highly sensitive method. Carotid arteries were subjected to duplex scanning. Results. PA patients had a high cardiovascular risk. Dyslipidemia manifested with a high total cholesterol, LDLP cholesterol which correlated with inflammation activity. PA was more frequently associated with subclinical atherosclerosis and atherosclerotic plaques. Conclusion. Chronic immune inflammation underlying pathogenesis of PA contributes to development of early atherosclerosis and its complications. A high cardiovascular risk is a constituent of PA which had an impact on long-term prognosis of this disease.

引用

页码：41 / 47

页数：7

共 26 条

[1] Plasma concentration of C-reactive protein and the calculated Framingham Coronary Heart Disease Risk Score [J].