Epidemiological study on hand, foot and mouth disease in Tongzhou District, Beijing, 2013-2017

被引:7
作者
Liu, Xiao-Feng [1 ]
Sun, Xiu-Mei [2 ]
Sun, Xiao-Wei [2 ]
Yang, Yu-Qing [2 ]
Huang, Cong-Hui [2 ]
Wen, Han [2 ]
机构
[1] Beijing Ctr Dis Prevent & Control, Adm Off, 16 Hepingli Middle St, Beijing 100013, Peoples R China
[2] Tongzhou Dist Ctr Dis Prevent & Control, Business Management Off, Beijing, Peoples R China
基金
中国国家自然科学基金;
关键词
Hand; foot and mouth disease; epidemiology; pathogen; enterovirus; children; infection; ENTEROVIRUS; 71; CHINA; EVOLUTION; SHENZHEN; HEALTH;
D O I
10.1177/0300060519841974
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Objective To study the epidemiological characteristics of hand, foot and mouth disease (HFMD) in Tongzhou District, Beijing between 2013 and 2017. Methods Data on HFMD infections from 1 January 2013 to 31 December 2017 were collected from the Notifiable Infectious Diseases Reporting Information System and analysed. Serotyping of enteroviruses from samples from patients with HFMD was undertaken using reverse transcription-polymerase chain reaction. Results A total of 15 341 patients with HFMD were reported and 32 patients (0.2%) were classified as having severe HFMD. The annual mean incidence rate of HFMD was 219.3/100 000 of the general population. The incidence and case-severity rates of HFMD generally decreased between 2013 and 2017. In the floating migrant population, the incidence and cases-severity rates of HFMD were significantly higher than in the local population. The peak incidence and severity-case rates were at 2 years of age and > 90% of patients were <= 5 years. Enterovirus A71 and Coxsackievirus A16 were the predominant pathogens in 2013-2017. Conclusions During the 5-year period 2013-2017, the incidence rate and case-severity rate of HFMD generally decreased in Tongzhou District, Beijing. The floating migrant population and children <= 5 years of age were at the highest risk of HFMD.
引用
收藏
页码:2615 / 2625
页数:11
相关论文
共 36 条
[11]   The Epidemiology of Hand, Foot and Mouth Disease in Asia A Systematic Review and Analysis [J].
Koh, Wee Ming ;
Bogich, Tiffany ;
Siegel, Karen ;
Jin, Jing ;
Chong, Elizabeth Y. ;
Tan, Chong Yew ;
Chen, Mark I. C. ;
Horby, Peter ;
Cook, Alex R. .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2016, 35 (10) :E285-E300
[12]   An automated genotyping tool for enteroviruses and noroviruses [J].
Kroneman, A. ;
Vennema, H. ;
Deforche, K. ;
v. d. Avoort, H. ;
Penaranda, S. ;
Oberste, S. ;
Vinje, J. ;
Koopmans, M. .
JOURNAL OF CLINICAL VIROLOGY, 2011, 51 (02) :121-125
[13]   Epidemiological and genetic analysis concerning the non-enterovirus 71 and non-coxsackievirus A16 causative agents related to hand, foot and mouth disease in Anyang city, Henan Province, China, from 2011 to 2015 [J].
Li, Yang ;
Bao, Honghong ;
Zhang, Xiangping ;
Zhai, Mingqiang ;
Bao, Xiaobing ;
Wang, Demin ;
Zhang, Shuanhu .
JOURNAL OF MEDICAL VIROLOGY, 2017, 89 (10) :1749-1758
[14]   Emerging Enteroviruses Causing Hand, Foot and Mouth Disease, China, 2010-2016 [J].
Li, Yu ;
Chang, Zhaorui ;
Wu, Peng ;
Liao, Qiaohong ;
Liu, Fengfeng ;
Zheng, Yaming ;
Luo, Li ;
Zhou, Yonghong ;
Chen, Qi ;
Yu, Shuanbao ;
Guo, Chun ;
Chen, Zhenhua ;
Long, Lu ;
Zhao, Shanlu ;
Yang, Bingyi ;
Yu, Hongjie ;
Cowling, Benjamin J. .
EMERGING INFECTIOUS DISEASES, 2018, 24 (10) :1902-1906
[15]   Clinical Features for Mild Hand, Foot and Mouth Disease in China [J].
Liu, Baoyan ;
Luo, Lin ;
Yan, Shiyan ;
Wen, Tiancai ;
Bai, Wenjing ;
Li, Hongjiao ;
Zhang, Guoliang ;
Lu, Xiaoying ;
Liu, Yan ;
He, Liyun .
PLOS ONE, 2015, 10 (08)
[16]   Characterization of an Outbreak of Hand, Foot, and Mouth Disease in Nanchang, China in 2010 [J].
Liu, Michelle Y. ;
Liu, Weiyong ;
Luo, Jun ;
Liu, Yingle ;
Zhu, Yang ;
Berman, Hillary ;
Wu, Jianguo .
PLOS ONE, 2011, 6 (09)
[17]   Co-Circulation and Genomic Recombination of Coxsackievirus A16 and Enterovirus 71 during a Large Outbreak of Hand, Foot, and Mouth Disease in Central China [J].
Liu, Weiyong ;
Wu, Shimin ;
Xiong, Ying ;
Li, Tongya ;
Wen, Zhou ;
Yan, Mingzhe ;
Qin, Kai ;
Liu, Yingle ;
Wu, Jianguo .
PLOS ONE, 2014, 9 (04)
[18]  
Lu B, 2014, LANCET INFECT DIS, V14, P1041, DOI 10.1016/S1473-3099(14)70973-9
[19]   Aseptic Meningitis in Children: Analysis of 506 Cases [J].
Michos, Athanasios G. ;
Syriopoulou, Vassiliki P. ;
Hadjichristodoulou, Christos ;
Daikos, George L. ;
Lagona, Evagelia ;
Douridas, Panagiotis ;
Mostrou, Glykeria ;
Theodoridou, Maria .
PLOS ONE, 2007, 2 (08)
[20]   Clinical features, diagnosis, and management of enterovirus 71 [J].
Ooi, Mong How ;
Wong, See Chang ;
Lewthwaite, Penny ;
Cardosa, Mary Jane ;
Solomon, Tom .
LANCET NEUROLOGY, 2010, 9 (11) :1097-1105