Genomic Profiling of Breast Cancer

被引：5
作者：
Pandey, Anjita
Singh, Alok Kumar
Maurya, Sanjeev Kumar
Rai, Rajani
Tewari, Mallika [1 ]
Kumar, Mohan [2 ]
Shukla, Hari S.
机构：
[1] Banaras Hindu Univ, Inst Med Sci, Dept Surg Oncol, Varanasi 221005, Uttar Pradesh, India
[2] Banaras Hindu Univ, Inst Med Sci, Dept Pathol, Varanasi 221005, Uttar Pradesh, India
来源：
JOURNAL OF SURGICAL ONCOLOGY | 2009年 / 99卷 / 06期
关键词：
tumor suppressor genes; proto-oncogenes; DNA repair genes; carcinogen metabolism genes; breast cancer; TUMOR-SUPPRESSOR GENE; MAMMARY EPITHELIAL-CELLS; DNA-REPAIR GENES; C-MYC; RETINOBLASTOMA PROTEIN; CARCINOGEN METABOLISM; IN-SITU; EXPRESSION; POLYMORPHISMS; METHYLATION;
D O I：
10.1002/jso.21249
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Genome study provides significant changes in the advancement of molecular diagnosis and treatment in Breast cancer. Several recent critical advances and high-throughput techniques identified the genomic trouble and dramatically accelerated the pace of research in preventing and curing this malignancy. Tumor-suppressor genes, Proto-oncogenes, DNA-repair genes, Carcinogen-metabolism genes are critically involved in progression of breast cancer. We reviewed imperative finding in breast genetics. ongoing work to segregate further susceptible genes, and preliminary studies on molecular profiling.
引用
收藏
页码：386 / 392
页数：7
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