Early and Late Outcomes of Operation for Acute Type A Aortic Dissection in Patients Aged 80 Years and Older

被引:27
作者
Omura, Atsushi [1 ]
Matsuda, Hitoshi
Minami, Hitoshi
Nakai, Hidekazu
Henmi, Soichiro
Murakami, Hirohisa
Yoshida, Masato
Mukohara, Nobuhiko
机构
[1] Hyogo Brain & Heart Ctr, Div Cardiovasc Surg, 520 Saisho Ko, Himeji, Hyogo 6700981, Japan
关键词
ELDERLY-PATIENTS; OCTOGENARIANS; SURGERY; REPAIR; POPULATION; MORTALITY; SURVIVAL;
D O I
10.1016/j.athoracsur.2016.05.046
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. The number of elderly patients undergoing emergency operation for acute type A aortic dissection is increasing in the aging society. We examined the early and late outcomes of operation for acute type A aortic dissection in elderly patients (>= 80 years old). Methods. From January 2001 to December 2015, 345 consecutive patients underwent surgical treatment for acute type A aortic dissection at our institution. Of these, 63 elderly patients (>= 80 years old; 28 men; mean age, 83.7 +/- 3.0 years) were reviewed and compared with nonelderly patients (<= 79 years old). Results. The hospital death was 9/63 (14.3%) and 25/282 (8.9%) in patients 80 years and older but 79 years or younger, respectively (p = 0.28). Multivariate analysis showed age 80 years or older was a significant risk factor for hospital mortality (odds ratio 3.27, 95% confidence interval: 1.22 to 8.76, p = 0.02). During follow-up period (mean, 51.3 +/- 40.9 months; range, 1 to 162 months), the 5year survival of the elderly patients discharged from the hospital was 58.6% +/- 8.7%. At postoperative 6 months and the latest follow-up (mean, 44.3 +/- 25.6 months) of the elderly patients excluding late death, 90.2% (46/51) and 88% (22/25) of elderly patients had totally or almost independent daily life, respectively. Conclusions. Although age 80 years or older was the risk factor for hospital mortality in operation for acute type A aortic dissection, the long-term survival of the hospital survivors and the level of activity of daily life were acceptable. Aggressive surgical treatment could be a reasonable option for selected elderly patients. (C) 2017 by The Society of Thoracic Surgeons
引用
收藏
页码:131 / 138
页数:8
相关论文
共 24 条
[1]   Surgical Repair for Acute Type A Aortic Dissection in Octogenarians [J].
Ahmad, Ali El-Sayed ;
Papadopoulos, Nestoras ;
Detho, Faisal ;
Srndic, Edin ;
Risteski, Petar ;
Moritz, Anton ;
Zierer, Andreas .
ANNALS OF THORACIC SURGERY, 2015, 99 (02) :547-551
[2]   Acute type A aortic dissection: long-term results and reoperations [J].
Bekkers, Jos A. ;
Raap, Goris Bol ;
Takkenberg, Johanna J. M. ;
Bogers, Ad J. J. C. .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2013, 43 (02) :389-396
[3]   National Outcomes in Acute Aortic Dissection: Influence of Surgeon and Institutional Volume on Operative Mortality [J].
Chikwe, Joanna ;
Cavallaro, Paul ;
Itagaki, Shinobu ;
Seigerman, Matthew ;
DiLuozzo, Gabrielle ;
Adams, David H. .
ANNALS OF THORACIC SURGERY, 2013, 95 (05) :1563-1569
[4]   Improved clinical outcomes and survival following repair of acute type A aortic dissection in the current era [J].
Conway, Brian D. ;
Stamou, Sotiris C. ;
Kouchoukos, Nicholas T. ;
Lobdell, Kevin W. ;
Khabbaz, Kamal R. ;
Murphy, Edward ;
Hagberg, Robert C. .
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY, 2014, 19 (06) :971-U233
[5]  
Etz C, 2013, EUR J CARDIO-THORAC, V44, P424
[6]   Comparing survival of a sample to that of a standard population [J].
Finkelstein, DM ;
Muzikansky, A ;
Schoenfeld, DA .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2003, 95 (19) :1434-1439
[7]   ADVENTITIAL INVERSION TECHNIQUE IN REPAIR OF AORTIC DISSECTION [J].
FLOTEN, HS ;
RAVICHANDRAN, PS ;
FURNARY, AP ;
GATELY, HL ;
STARR, A .
ANNALS OF THORACIC SURGERY, 1995, 59 (03) :771-772
[8]   Should emergency surgical intervention be performed for an octogenarian with type A acute aortic dissection? [J].
Hata, Mitsumasa ;
Sezai, Akira ;
Niino, Tetsuya ;
Yoda, Masataka ;
Unosawa, Satoshi ;
Furukawa, Nobuyuki ;
Osaka, Shunji ;
Murakami, Tomohiko ;
Minami, Kazutomo .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2008, 135 (05) :1042-1046
[9]   Midterm Outcomes of Rapid, Minimally Invasive Resection of Acute Type A Aortic Dissection in Octogenarians [J].
Hata, Mitsumasa ;
Sezai, Akira ;
Yoshitake, Isamu ;
Wakui, Shinji ;
Minami, Kazutomo ;
Shiono, Motomi .
ANNALS OF THORACIC SURGERY, 2010, 89 (06) :1860-1865
[10]   Risk analysis and improvement of strategies in patients who have acute type A aortic dissection with coronary artery dissection [J].
Imoto, Kiyotaka ;
Uchida, Keiji ;
Karube, Norihisa ;
Yasutsune, Toru ;
Cho, Tonoki ;
Kimura, Kazuo ;
Masuda, Munetaka ;
Morita, Satoshi .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2013, 44 (03) :419-424