Chromium Exposure and Germinal Embryonal Carcinoma: First Two Cases and Review of the Literature

被引：14

作者：

Berardi, Rossana ^{[1
]}

Pellei, Chiara ^{[1
]}

Valeri, Gianluca ^{[1
]}

Pistelli, Mirco ^{[1
]}

Onofri, Azzurra ^{[1
]}

Morgese, Francesca ^{[1
]}

Caramanti, Miriam ^{[1
]}

Mirza, Riccardo Mashadi ^{[1
]}

Santoni, Matteo ^{[1
]}

De Lisa, Mariagrazia ^{[1
]}

Savini, Agnese ^{[1
]}

Ballatore, Zelmira ^{[1
]}

Giuseppetti, Gian Marco ^{[1
]}

Cascinu, Stefano ^{[1
]}

机构：

[1] Univ Politecn Marche, Azienda Osped Univ Osped Riuniti Umberto I GM Lan, I-60126 Ancona, Italy

来源：

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES | 2015年 / 78卷 / 01期

关键词：

PROGNOSTIC-FACTORS; CELL TUMORS; INFLAMMATION; POPULATION; DISEASE; CANCER;

D O I：

10.1080/15287394.2015.958416

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The aim of the study was to determine the potential role of occupational exposures to chromium (Cr) in the onset of extragonadal germinal embryonal carcinoma. The first two cases of workers in a company with Cr exposure are reported. The published scientific literature regarding the topic in peer-reviewed journals including MEDLINE and CancerLit databases was extensively reviewed. Two young patients who were coworkers in the same company, exposed to Cr, developed extragonadal germinal embryonal carcinomas. One of them also developed angiosarcoma of the mediastinum. To the best of our knowledge these are the first two cases of germinal embryonal carcinoma in patients with occupational exposure to Cr.

引用

页码：1 / 6

页数：6

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