An Emerging Role for Metabolomics in Nutrition Science

被引：67

作者：

Astarita, Giuseppe ^{[1
,2
]}

Langridge, James ^{[1
]}

机构：

[1] Waters Corp, Discovery & Life Sci, Milford, MA 01757 USA

[2] Georgetown Univ, Dept Biochem & Mol & Cellular Biol, Washington, DC USA

来源：

JOURNAL OF NUTRIGENETICS AND NUTRIGENOMICS | 2013年 / 6卷 / 4-5期

关键词：

Metabolomics; Lipidomics; Food; Diet; Nutrition; Lipids; Metabolites; Mass spectrometry; POLYUNSATURATED FATTY-ACIDS; DOCOSAHEXAENOIC ACID; MASS-SPECTROMETRY; SYSTEMS BIOLOGY; FISH-OIL; ENVIRONMENTAL METABOLOMICS; COLONIC MICROBIOTA; MEDITERRANEAN DIET; FOOD-SCIENCE; HEALTH;

D O I：

10.1159/000354403

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Nutritional research is undergoing a remarkable transformation driven by new technological tools. Because of the complexity of the components present in food and how they may interact with the biochemical networks of living organisms, nutrition cannot be considered a reductionist discipline. More holistic approaches, which are capable of gathering comprehensive, high-throughput amounts of data, appear to best enhance our understanding of the role of food in health and disease. In this context, global metabolite analysis, or 'metabolomics', is becoming an appealing research tool for nutrigenomics and nutrigenetics scientists. The purpose of the present review is to highlight some potential applications of metabolomics in nutrition research. (C) 2013 S. Karger AG, Basel

引用

页码：181 / 200

页数：20

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